Catalogue


RNA nanotechnology and therapeutics /
edited by Peixuan Guo, Farzin Haque.
imprint
Boca Raton, FL : CRC Press, Taylor & Francis Group [2014]
description
xvii, 593 pages : illustrations (some color) ; 26 cm.
ISBN
1466505664 (hardcover : alk. paper), 9781466505667 (hardcover : alk. paper)
format(s)
Book
Holdings
More Details
imprint
Boca Raton, FL : CRC Press, Taylor & Francis Group [2014]
isbn
1466505664 (hardcover : alk. paper)
9781466505667 (hardcover : alk. paper)
catalogue key
9049467
 
Includes bibliographical references and index.
A Look Inside
Reviews
Review Quotes
"The main strength of this book is in its focus on RNA as a functional agent. RNA can be derivatized using a variety of biochemical technologies to incorporate therapeutic or imaging functionalities. This book spans different aspects of techniques that are necessary to obtain functional RNA nanoparticles, including computational design, synthesis of components, assembly of functional units, and their biochemical and biophysical characterization. It also discusses promises and challenges in the applications of RNA nanoparticles as therapeutics. … This book is unique in that it covers a very broad spectrum of topics related to RNA nanotechnology, yet it maintains a focus on constructing and analyzing RNA nanoparticles. It introduces the reader to the basics of RNA structure, and discusses functions of various natural RNAs, from small molecules to large molecular machines such as the ribosome. It also introduces the concept of designing new RNAs, and provides a comprehensive coverage of modern techniques, linking theory and experiment. Technologies discussed include RNA structure prediction, prediction of interactions, simulations of RNA folding, computational design, chemical methods for RNA nanoparticle synthesis, assembly, and labeling, as well as methods for their biophysical and biochemical characterization and biomolecular imaging. … Chapters 1, 4, 7 are very exciting. Chapter 1 is a condensed introduction to the topic of RNA nanotechnology and to challenges and opportunities in using the RNA molecules as therapeutic agents. It is quite obvious that Dr. Guo is an enthusiast of RNA nanotechnology and in fact, this enthusiasm is quite contagious. Chapters 4 and 7 provide more focused description of two issues: 1) naturally existing RNAs as molecular machines, with a very informative discussion of differences between molecular machines and macro-machines, using ribosome as an example and 2) the role of dynamics (as opposed to 3D structure alone) in RNA design. Both these chapters demonstrate the extraordinary interdisciplinary character of the field of RNA nanotechnology, as well asof this very book. I definitely want to have this book on my shelf, and I intend to read all chapters as soon as I get it!" Prof. Janusz M. Bujnicki, International Institute of Molecular and Cell Biology in Warsaw, and Adam Mickiewicz University in Pozna, Poland
"The main strength of this book is in its focus on RNA as a functional agent. RNA can be derivatized using a variety of biochemical technologies to incorporate therapeutic or imaging functionalities. This book spans different aspects of techniques that are necessary to obtain functional RNA nanoparticles, including computational design, synthesis of components, assembly of functional units, and their biochemical and biophysical characterization. It also discusses promises and challenges in the applications of RNA nanoparticles as therapeutics. ... This book is unique in that it covers a very broad spectrum of topics related to RNA nanotechnology, yet it maintains a focus on constructing and analyzing RNA nanoparticles. It introduces the reader to the basics of RNA structure, and discusses functions of various natural RNAs, from small molecules to large molecular machines such as the ribosome. It also introduces the concept of designing new RNAs, and provides a comprehensive coverage of modern techniques, linking theory and experiment. Technologies discussed include RNA structure prediction, prediction of interactions, simulations of RNA folding, computational design, chemical methods for RNA nanoparticle synthesis, assembly, and labeling, as well as methods for their biophysical and biochemical characterization and biomolecular imaging. ... Chapters 1, 4, 7 are very exciting. Chapter 1 is a condensed introduction to the topic of RNA nanotechnology and to challenges and opportunities in using the RNA molecules as therapeutic agents. It is quite obvious that Dr. Guo is an enthusiast of RNA nanotechnology and in fact, this enthusiasm is quite contagious. Chapters 4 and 7 provide more focused description of two issues: 1) naturally existing RNAs as molecular machines, with a very informative discussion of differences between molecular machines and macro-machines, using ribosome as an example and 2) the role of dynamics (as opposed to 3D structure alone) in RNA design. Both these chapters demonstrate the extraordinary interdisciplinary character of the field of RNA nanotechnology, as well asof this very book. I definitely want to have this book on my shelf, and I intend to read all chapters as soon as I get it!" --Prof. Janusz M. Bujnicki, International Institute of Molecular and Cell Biology in Warsaw, and Adam Mickiewicz University in Pozna, Poland "This book is very good in this field. I want to have this book on my shelf. ... This book has a broad coverage from principles and fundamentals of RNA nanotechnology, RNA nanotechnology design and construction to diagnostic and therapeutic application. These detailing descriptions provide a clear and complete picture of up-to-date knowledge of RNA nanotechnology and applications." --Prof. Shu-Feng Zhou, University of South Florida
To find out how to look for other reviews, please see our guides to finding book reviews in the Sciences or Social Sciences and Humanities.
Summaries
Bowker Data Service Summary
Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world's foremost experts in nanomedicine, this comprehensive, state-of-the-art reference details the latest research developments and challenges in the biophysical and single molecule approaches in RNA nanotechnology.
Main Description
Interest in RNA nanotechnology has increased in recent years as recognition of its potential for applications in nanomedicine has grown. Edited by the world's foremost experts in nanomedicine, this comprehensive, state-of-the-art reference details the latest research developments and challenges in the biophysical and single molecule approaches in RNA nanotechnology. In addition, the text also provides in-depth discussions of RNA structure for nanoparticle construction, RNA computation and modeling, single molecule imaging of RNA, RNA nanoparticle assembly, RNA nanoparticles in therapeutics, RNA chemistry for nanoparticle synthesis, and conjugation and labeling.

This information is provided by a service that aggregates data from review sources and other sources that are often consulted by libraries, and readers. The University does not edit this information and merely includes it as a convenience for users. It does not warrant that reviews are accurate. As with any review users should approach reviews critically and where deemed necessary should consult multiple review sources. Any concerns or questions about particular reviews should be directed to the reviewer and/or publisher.

  link to old catalogue

Report a problem