Catalogue


Comparative effectiveness of warfarin and newer oral anticoagulants for the long-term prevention and treatment of arterial and venous thromboembolism [electronic resource] /
prepared for, Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by, Evidence-based Synthesis Program (ESP) Center, Durham Veterans Affairs Healthcare System ; investigators, Soheir S. Adam ... [et al.].
imprint
Washington, DC : Department of Veterans Affairs, Health Services Research and Development Service, 2012.
description
1 online resource (PDF file (iv, 115 p.)) : ill.
format(s)
Book
Holdings
More Details
added author
imprint
Washington, DC : Department of Veterans Affairs, Health Services Research and Development Service, 2012.
restrictions
Licensed for access by U. of T. users.
general note
"April 2012."
abstract
The Veterans Health Administration (VHA) System serves a largely older, male population with a high prevalence of chronic atrial fibrillation (AF) and venous thromboembolism (VTE). Many veterans with chronic AF have risk profiles for stroke that, according to current clinical guidelines, place them in a risk group where chronic anticoagulation is recommended. Adjusted-dose warfarin has been the preferred approach to chronic anticoagulation in the VHA, and in many VHA settings, specialized therapeutic drug-monitoring services provide high-quality warfarin treatment. However, the advent of newer anticoagulants with the promise of simplified long-term anticoagulation requires reconsideration of current treatment practices. The purpose of this systematic review was to study the comparative effectiveness of warfarin and the newer oral anticoagulants used for the long-term prevention and treatment of arterial and venous thromboembolism. An evaluation of newer oral anticoagulants for VTE prophylaxis in the perioperative period will be the subject of a later report.
catalogue key
9036487
 
Includes bibliographical references.
Prepared for: Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service, Washington, DC 20420. Prepared by: Evidence-based Synthesis Program (ESP) Center, Durham Veterans Affairs Healthcare System, Durham, NC, John W. Williams Jr., M.D., M.H.Sc., Director.

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