Catalogue


Structural glycobiology /
edited by Elizabeth Yuriev, Paul A. Ramsland.
imprint
Boca Raton, Fla. : CRC Press, c2013.
description
xiv, 309 p., [24] p. of plates : ill. (some col.) ; 24 cm.
ISBN
1439854602 (hardcover : alk. paper), 9781439854600 (hardcover : alk. paper)
format(s)
Book
Holdings
More Details
imprint
Boca Raton, Fla. : CRC Press, c2013.
isbn
1439854602 (hardcover : alk. paper)
9781439854600 (hardcover : alk. paper)
contents note
Crystallography and small-angle scattering of carbohydrate-protein complexes and glycoproteins / Cy M. Jeffries, William Farrugia, and Paul A. Ramsland -- Nuclear magnetic resonance studies of carbohydrate-protein interactions / Leonardus M.I. Koharudin and Angela M. Gronenborn -- Electron cryomicroscopy of large glycoprotein assemblies / Tzviya Zeev-Ben-Mordehai and Kay Grünewald -- Protein-carbohydrate interactions : computational aspects / Anita Sarkar and Serge Pérez -- Docking of carbohydrates into protein-binding sites / Mark Agostino, Paul A. Ramsland, and Elizabeth Yuriev -- Mass spectrometry for glycomics analysis of N- and O-linked glycoproteins / Daniel Kolarich and Nicolle H. Packer -- Glycan-based arrays for determining specificity of carbohydrate-binding proteins / Xuezheng Song, David F. Smith, and Richard D. Cummings -- Structural glycobiology : applications in cancer research / Inka Brockhausen and Yin Gao -- Structural glycobiology : applications in organ transplantation / Dale Christiansen ... [et al.] -- Structural glycobiology : applications in viral infection / Rui Xu and Ian A. Wilson -- Developing drugs from sugars current state of glycosaminoglycan-derived therapeutics / Neha S. Gandhi and Ricardo L. Mancera.
catalogue key
8679162
 
Includes bibliographical references and index.
A Look Inside
Reviews
This item was reviewed in:
Reference & Research Book News, December 2012
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Summaries
Bowker Data Service Summary
Structural glycobiology is a rapidly growing field of research that examines the structural and functional roles of carbohydrates. This book investigates how research findings have revealed key structural and associated biological information on carbohydrates and glycolipids.
Main Description
Structural Glycobiologycovers the experimental, theoretical, and alternative technologies used in the study of the structural basis for the diverse biological roles of carbohydrates. The book overviews the application of specialized technologies to the study of carbohydrates in biology, reviews relevant and current research in the field, and is illustrated throughout by specific examples of how research investigations have yielded key structural and associated biological data on carbohydrates and glycolipids. In particular, the book focuses on: X-ray crystallography and small-angle scattering, NMR, and cryo-electron microscopy techniques Theoretical (modeling-based) approaches, such as molecular mechanics, molecular dynamics, free energy calculations, and carbohydrate docking Alternative techniques for yielding structural information on carbohydrates from complex biological samples Carbohydrates in medicine, specifically in areas that have been directly impacted by our understanding of the structural role of carbohydrates in immune recognition: cancer, organ transplantation, and infection
Main Description
Structural glycobiology is a rapidly growing field of research that examines the structural and functional roles of carbohydrates. This book investigates how research findings have revealed key structural and associated biological information on carbohydrates and glycolipids. The first part focuses on theoretical and modeling-based approaches. The second part presents well-established experimental approaches for the structural determination of carbohydrate-protein complexes and large glycoprotein assemblies. The final part covers alternative and emerging techniques for yielding structural information on carbohydrates from complex biological samples.
Table of Contents
Experimental Techniques to Determine Three-Dimensional Structures
Crystallography and Small-Angle Scattering of Carbohydrate-Protein Complexes and Glycoproteins
Nuclear Magnetic Resonance Studies of Carbohydrate-Protein Interactions
Electron Cryomicroscopy of Large Glycoprotein Assemblies
Theoretical/Modeling Techniques to Predict Three-Dimensional Structures
Protein-Carbohydrate Interactions: Computational Aspects
Docking of Carbohydrates into Protein Binding Sites
Alternative Approaches for Yielding Detailed Structural Information
Mass Spectrometry for Glycomics Analysis of N- and O-Linked Glycoproteins
Glycan-Based Arrays for Determining Specificity of Carbohydrate-Binding Proteins
Carbohydrates in Medicine
Structural Glycobiology: Applications in Cancer Research
Structural Glycobiology: Applications in Organ Transplantation
Structural Glycobiology: Applications in Viral Infection
Developing Drugs from Sugars Current State of Glycosaminoglycan-Derived Therapeutics
Table of Contents provided by Publisher. All Rights Reserved.

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