Catalogue


Medicine, science, and Merck [electronic resource] /
P. Roy Vagelos, Louis Galambos.
imprint
Cambridge, UK ; New York : Cambridge University Press, 2004.
description
xi, 301 p. : ill., ports. ; 24 cm.
ISBN
0521662958 (hc), 9780521662956 (hc)
format(s)
Book
Subjects
geographic term
personal subject
corporate subject
genre index term
More Details
added author
imprint
Cambridge, UK ; New York : Cambridge University Press, 2004.
isbn
0521662958 (hc)
9780521662956 (hc)
restrictions
Licensed for access by U. of T. users.
general note
Includes index.
catalogue key
8367092
A Look Inside
About the Author
Author Affiliation
P. Roy Vagelos is retired Chairman of Merck & Co., Inc.; Chairman of Regeneron Pharmaceuticals, Inc.; and Chairman of Theravance Corporation Louis Galambos is Professor of History at the Johns Hopkins University in Baltimore
Full Text Reviews
Appeared in Choice on 2004-11-01:
Written with the assistance of Galambos (history, Johns Hopkins), this fascinating personal account follows Vagelos's medical sciences career during the 1950s-70s. The purely autobiographical portions are of marginal historical interest. However, the text is rich in describing medical research that sought treatments for chronic illness, neurological and psychiatric illnesses, heart disease, and viral infections. At the National Institutes of Health, Vagelos focused on research into the biochemistry of life changes. Once researchers could identify the enzymes responsible for molecular changes creating diseased conditions at the cellular level, they could develop chemical inhibitors to block the manifestation of illness. Targeting enzymes led Vagelos to research the metabolism of fatty acids, which eventually resulted in effective medications for a wide variety of diseases. After working at the Washington University School of Medicine, Vagelos headed the research division at Merck before becoming CEO. Besides providing an interesting window into changing approaches to biomedical research, this book is good business history. Vagelos describes structural changes he initiated at Merck. He makes a strong case for institutional autonomy of the pharmaceutical industry against government price controls of drugs. Though Vagelos's interpretation of the role of government in medicine should be counterbalanced with other perspectives, the book offers a starting point. ^BSumming Up: Recommended. All levels. J. P. Brickman United States Merchant Marine Academy
Reviews
Review Quotes
"Like so much of America, Medicine, Science, and Merck is, on the one hand, an intriguing story about an extraordinary American and a great American company. On the other and more importantly, it is also an intersecting and overlapping set of narratives about immigrants in America, medicine as a profession and an industry, and public policy that somehow transcends the fascinating story of an extraordinary American. Indeed this book succeeds in telling us a good deal about both ourselves and the nature of an important set of public policy issues that continue to grasp the public imagination and remain unresolved." Harold T. Shapiro, President Emeritus and Professor of Economics and Public Affairs, Princeton University
"Roy Vagelos is a universally admired leader, and he has used his rare gifts of energy, creativity and idealism to profoundly affect our world. I encourage everyone to read the inside story of his central role in developing some of the most exciting, lifesaving innovations in modern medicine where he functioned in the combined role of scientist and model CEO." Bruce Alberts, President, National Academy of Sciences
"...this book is good business history...makes a strong case for institutional autonomy of the pharmaceutical industry against government price controls of drugs." J.P. Brickman, United States Merchant Marine Academy, Choice
"This journey shines with optimism for all of us who have become demoralized by the failure of the ideals of science, medicine, and the corporate world and by the threat of defeat of our shared ethical vision. The book also gives heart to the reader to take a similar journey, assessing its enduring values, measuring its missed opportunities, admiring its texture." New England Journal
"...a very important book...a seemless weave of many stories...tremendous nourishment." Rita Charon, Professor of Clinical Medicine, Columbia University
"A wonderful book about how one individual's values and vision have shaped one of America's most innovative companies. It is a tale that ranges from the fight against AIDS to the discovery of lifesaving heart medicines. Read this book, and you'll understand more about modern medicine, public health and how private sector science benefits mankind everyday." Former Senator Bill Bradley
"If you want the real story on the pharmaceutical industry, Medicine, Science and Merck is the best place to start. Vagelos and Galambos tell us what it takes to be an innovator in an American industry that has long been the world's leading source of new drugs and vaccines." William C. Steere, Chairman of the Board Emeritus, Pfizer Inc.
This item was reviewed in:
Choice, November 2004
To find out how to look for other reviews, please see our guides to finding book reviews in the Sciences or Social Sciences and Humanities.
Summaries
Description for Bookstore
The authors trace the careers of a son of Greek immigrants as he mastered three professions and ultimately became the Chief Executive Officer of the pharmaceutical giant, Merck & Co., Inc. As the book shows, there was hope even for a wise-cracking kid living through the hard times of the 1930s.
Main Description
In Medicine, Science, and Merck, the authors trace the careers of a son of Greek immigrants as he mastered three professions and ultimately became the Chief Executive Officer of America's most admired corporation - the multinational, pharmaceutical giant, Merck & Co., Inc. As the authors show, there was hope even for a wise-cracking kid living through the hard times of the 1930s. Education brought out the scholar in Roy Vagelos, who left his family's small restaurant to attend the University of Pennsylvania, Columbia's Medical School, and Massachusetts General Hospital in Boston. At NIH, he mastered biochemistry; at Washington University he became a distinguished science administrator; and at Merck, he headed the pharmaceutical industry's most innovative laboratory and then became its CEO. Throughout, he never lost touch with his family values, his intense desire to help others, or his faith in the partnership principle and the competition that makes it work.
Description for Library
In Medicine, Science, and Merck, the authors trace the careers of a son of Greek immigrants as he mastered three professions and ultimately became the Chief Executive Officer of America's most admired corporation - the multinational, pharmaceutical giant, Merck & Co., Inc. As the authors show, there was hope even for a wise-cracking kid living through the hard times of the 1930s. Education brought out the scholar in Roy Vagelos, who left his family's small restaurant to attend the University of Pennsylvania, Columbia's Medical School, and Massachusetts General Hospital in Boston.
Main Description
P. Roy Vagelos grew up during the Depression as a wise-cracking son of Greek immigrants. He left his family's small restaurant to become a doctor and went on to master three professions and become the Chief Executive Officer of the multinational pharmaceutical giant, Merck & Co. Medicine, Science, and Merck follows Vangelos' life from childhood to retirement, from his academic years at the University of Pennsylvania, Columbia University's Medical School, and Massachusetts General Hospital through his professional career at the National Institute of Health, Washington University, and Merck. Throughout, Vagelos never lost touch with his family values, his intense desire to help others, and his faith in the partnership principle and the competition that makes it work. P. Roy Vagelos and Louis Galambos offer an unusual perspective on working in three leading professions: medicine, science, and business. They take readers inside the laboratory and boardroom of one of America's large corporations, analyzing the mistakes and the innovations of Merck. P. Roy Vagelos, M.D. served as CEO of Merck & Co., Inc. from 1985 to 1994. Before assuming responsibilities in business leadership, he had won scientific recognition as an authority on lipids and enzymes and as a research manager. The author of more than 100 scientific papers, Vagelos has been elected to the American Academy of Arts and Sciences, the National Academy of Sciences and the American Philosophical Society. Louis Galambos has written extensively on U.S. business-government relations, on economic aspects of modern institutional developments and on the rise of the bureaucratic state. A professor at Johns Hopkins University, Professor Galambos is the author of several books, including Anytime, Anywhere (Cambridge, 2002).
Bowker Data Service Summary
The son of Greek immigants, Roy Vagelos left the family restaurant to study medicine, biochemistry & then head up a pharmaceutical laboratory at Merck. Ultimately he became CEO of Merck.
Description for Bookstore
In Medicine, Science, and Merck, the authors trace the careers of a son of Greek immigrants as he mastered three professions and ultimately became the Chief Executive Officer of America's most admired corporation, the multinational, pharmaceutical giant, Merck & Co., Inc. As the authors show, there was hope even for a wise-cracking kid living through the hard times of the 1930s. Education brought out the scholar in Roy Vagelos, who left his family's small restaurant to attend the University of Pennsylvania, Columbia's Medical School, and Massachusetts General Hospital in Boston.
Table of Contents
Prefacep. ix
The Making of a Physicianp. 1
Hot Science in Big Governmentp. 37
The French Alternativep. 58
The Research University--American Stylep. 74
Turning the Corner at Merckp. 106
Crisisp. 139
Blockbustersp. 152
On-the-Job Trainingp. 175
Global Aspirationsp. 195
The Moral Corporationp. 225
Getting to Know the Clintonsp. 257
Partnersp. 272
Indexp. 293
Table of Contents provided by Ingram. All Rights Reserved.

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