Catalogue


Atlas of endomicroscopy [electronic resource] /
[editors] Ralf Kiesslich, Peter R. Galle, Markus F. Neurath.
imprint
Heidelberg : Springer, c2008.
description
xiv, 103 p. : 156 fig. (partly col.), 8 tab. ; 25 cm.
ISBN
3540347577, 9783540347576
format(s)
Book
Subjects
genre index term
More Details
imprint
Heidelberg : Springer, c2008.
isbn
3540347577
9783540347576
restrictions
Licensed for access by U. of T. users.
catalogue key
7840311
 
Includes bibliographical references and index.
A Look Inside
Reviews
This item was reviewed in:
Doody's Reviews, May 2008
To find out how to look for other reviews, please see our guides to finding book reviews in the Sciences or Social Sciences and Humanities.
Summaries
Main Description
Endomicroscopy is a newly developed diagnostic tool that enables in vivo microscopy with subcellular resolution during ongoing endoscopy in the upper and lower gastrointestinal tract. It is a revolutionary technology. Endoscopy and pathology are no longer separate subjects and, as a result, endomicroscopy leads to a close interaction between endoscopist and pathologist. This Atlas of Endomicroscopy is the first book dealing with the new insights of endomicroscopy. It provides an overview about the development, the requirements, the technique, current indications and further possibilities of endomicroscopy.
Bowker Data Service Summary
This title deals with the new insights of endomicroscopy and provides the reader with an overview about the development, requirements, technique, current indications and further possibilities of endomicroscopy.
Long Description
Endomicroscopy is a newly developed diagnostic tool which enables in vivo microscopy with subcellular resolution during ongoing endoscopy in the upper and lower gastrointestinal tract. Thus, endomicroscopy is a revolutionary technology because it provides the endoscopists for the first time with information about living cells in humans. Endoscopy and pathology are no longer separate subjects and thus endomicroscopy leads to a close interaction between endoscopist and pathologist. This Atlas of Endomicroscopy is the first book dealing with the new insights of endomicroscopy and provides you an overview about the development, the requirements, the technique, current indications and further possibilities of endomicroscopy.
Table of Contents
Development of Endoscopic Devices: Past, Present and Futurep. 1
Introductionp. 1
The Presentp. 2
The Futurep. 3
Referencesp. 6
Surface Analysis with Magnifying Chromoendoscopy in the Colonp. 7
Backgroundp. 7
Classification of Superficial Neoplastic Colorectal Neoplasia - a Consensus Workshop Approachp. 8
Stereomicroscopy and 'Pit Patterns' in the Human Colonp. 9
Pit-pattern Classification and Magnification-Chromoscopic Appearancesp. 9
Magnification Chromoscopy in Routine Clinical Practicep. 9
Current Endoluminal In Vivo Imaging Techniquesp. 10
Limitations and Data Summaryp. 10
In Vivo Staging of Colorectal Lesions Using Magnifying Chromoendoscopyp. 10
Summary of Limitations of Current Technologyp. 12
Chromoscopic Colonoscopy and Magnifying Chromoendoscopy Imaging as an Adjunctive Screening Tool in Colitisp. 12
Clinical Recommendations and Conclusionsp. 13
Referencesp. 14
Development and Current Technological Status of Confocal Laser Endomicroscopyp. 17
Introductionp. 17
Principles of Confocal Microscopyp. 18
Miniaturisation - Fibre-Optic Confocal Microscopyp. 19
Current Technology in the flexible Gl endomicroscopep. 20
Current Technology - Key Features for Endomicroscopy of the Gl Tractp. 21
Summary and [double right angle bracket]Take-home[double left angle bracket] messagesp. 22
Referencesp. 22
Examination Technique of Confocal Laser Endomicroscopyp. 25
Introductionp. 25
The Confocal Endomicroscopep. 25
Patient Preparationp. 27
In Vivo Confocal Imagingp. 28
Fluorescent Agentsp. 30
Referencesp. 31
The Technique of Confocal Laser Endomicroscopy from the Perspective of a New Userp. 33
Introductionp. 33
Preparation for Endomicroscopic Imagingp. 33
Entering Case Data and Imaging Sitesp. 33
Study the Control Screenp. 34
Check the Laser and Calibratep. 34
Obtaining Informed Consentp. 35
General Technique of Confocal Endomicroscopic Imagingp. 36
Targeting of a Lesion or Areap. 36
Achieving Contact of the Confocal Window with the Mucosap. 36
Acquiring a Stable Positionp. 36
Performing Endomicroscopic Imagingp. 36
Planning the Anatomical Sites for Endomicroscopic Imagingp. 36
Identifying and Minimising Image Artefactp. 37
Limitationsp. 38
Image Annotation, Export, Archive and Reviewp. 38
Annotating Imagesp. 38
Saving and Exporting Imagesp. 38
Reviewing Imagesp. 38
Microarchitecture of the Normal Gut Seen with Conventional Histology and Endomicroscopyp. 39
Introductionp. 39
General Structure and Components of the Gastrointestinal Tractp. 39
Mucosal Layerp. 40
Oesophagusp. 40
Endomicroscopic Imaging of Normal Oesophageal Mucosap. 43
Stomachp. 43
Endomicroscopic Imaging of Gastric Mucosap. 44
Small Bowelp. 46
Endomicroscopic Imaging of Small Bowel Architecturep. 47
Colonp. 48
Endomicroscopic Imaging of Colonic Mucosap. 49
Lymphoid Tissuep. 51
Innervationp. 52
Endocrine Cellsp. 53
Vasculaturep. 53
Conclusionp. 53
Referencesp. 54
Endomicroscopy of Gl Disordersp. 55
Endomicroscopy in Early Oesophageal Squamous Cell Neoplasiasp. 55
Referencesp. 57
Barrett's Oesophagusp. 57
Referencep. 59
Endomicroscopy of Gastritis and Gastric Cancerp. 60
Normal Gastric Microarchitecturep. 60
Gastritisp. 60
Intestinal Metaplasiap. 61
Helicobacter pylori-positive Gastritisp. 61
Early Gastric Cancerp. 63
Referencesp. 66
Endomicroscopy of Small Bowel Diseases: Coeliac Disease, Lymphomap. 66
Coeliac Diseasep. 66
Gastrointestinal Lymphomap. 67
Mantle-cell Lymphomap. 68
Proliferations of Acquired MALTp. 69
Referencesp. 70
Endomicroscopy of Colon Pathologyp. 70
Ulcerative Colitisp. 72
Microscopic Colitisp. 75
Referencesp. 76
Endomicroscopy in Acute Graft-versus-Host Diseasep. 76
Referencesp. 77
Live Tissue Imaging with Conventional Confocal Microscopyp. 79
A Primer on Laser-Scanning Confocal Imagingp. 79
Imaging Fixed Versus Living Tissuep. 80
Going from Qualitative to Quantitativep. 83
Moving Beyond Confocal Imagingp. 83
Selecting the Correct Instrument for the Task at Handp. 84
Translational Research Abilityp. 84
Multicolour Fluorescencep. 84
Maximal Subcellular Resolutionp. 84
Wide Field of View and Sporadic Events/Structuresp. 84
More Flexible Imaging Parameters in Confocal Microscopyp. 84
Conclusionp. 84
Referencep. 85
Functional and Molecular Imaging with Confocal Laser Endomicroscopyp. 87
Aims of Functional and Molecular Imagingp. 87
Functional Imagingp. 87
Molecular Imagingp. 90
Referencesp. 91
Future Trends in Confocal Laser Endomicroscopy: Improved Imaging Quality and Immunoendoscopyp. 93
Introductionp. 93
Characterisation of Antibodies as Diagnostic and Research Instrumentsp. 94
Antibody Structurep. 94
Diagnostic Monoclonal and Polyclonal Antibodiesp. 94
Therapeutic Monoclonal Antibodiesp. 95
Immunhistochemistryp. 96
Direct Immunostainingp. 96
Indirect Immunostainingp. 96
Immunofluorescencep. 97
In Vivo Fluorescence Endomicroscopy for Immunoendoscopyp. 98
In Vivo Fluorescence Endomicroscopy in Inflammatory Bowel Diseasep. 98
In Vivo Fluorescence Endomicroscopy in Cancer Treatmentp. 99
Conclusionp. 99
Referencesp. 99
Subject Indexp. 101
Table of Contents provided by Ingram. All Rights Reserved.

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