Catalogue


Enzybiotics : antibiotic enzymes as drugs and therapeutics /
edited by Tomas G. Villa and Patricia Veiga-Crespo.
imprint
Hoboken, N.J. : Wiley, c2010.
description
x, 284 p.
ISBN
0470376554 (cloth), 9780470376553 (cloth)
format(s)
Book
Holdings
More Details
imprint
Hoboken, N.J. : Wiley, c2010.
isbn
0470376554 (cloth)
9780470376553 (cloth)
contents note
Enzybiotics and their potential applications in medicine / Jan Borysowski and Andrzej Górski -- Advantages and disadvantages in the use of antibiotics or phages as therapeutical agents / T.G. Villa and P. Veiga-Crespo -- Enzybiotics for use in selectively killing target bacteria / Juan C. Alonso and Marcelo Tolmasky -- Phylogeny of enzybiotics / T.G. Villa and P. Veiga-Crespo -- Bacteriophage lytic enzymes : novel anti-infectives to control gram-positive pathogens / Vincent A. Fischetti -- Bacteriophages holins and their membrane disrupting activity / Maria Gasset -- Anti-staphylococcal lytic enzymes / Jan Borysowski and Andrzej Górski -- Membrane-targeted enzybiotics / Maria Gasset -- Design of phage cocktails for therapy from a host range point of view / Lawrence Goodridge -- Identifying phage lytic enzymes : past, present, and future / Jonathan E. Schmitz, Raymond Schuch, and Vincent A. Fischetti -- Use of genetically modified phages to deliver suicidal genes to target bacteria / Lawrence Goodridge.
general note
Includes index.
catalogue key
7029820
A Look Inside
About the Author
Author Affiliation
Thomas G. Villa, PhD, is Full Professor of Microbiology and Chair of the Department of Microbiology at the University of Santiago de Compostela, Faculty of Pharmacy (Spain). Dr. Villa has written twenty book chapters and over 160 papers. In addition, he has translated into Spanish several microbiology text books. Dr. Villa is regularly engaged in the teaching of microbiology and biotechnology. Patricia Veiga-Crespo, PhD, is Lecturer of Microbiology and works in the Department of Microbiology at the University of Santiago de Compostela, where she is involved in the study of multi-resistance phenomena and ezybiotics and the teaching of advanced biotechnology and basic microbiology.
Summaries
Long Description
Presents the latest research and applications for a new, promising approach to fighting infectious diseasesEnzybiotics is a promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry, microbiology, genetics, and biochemistry, this book presents the state of the science in enzybiotics research, fully exploring its emerging therapeutic applications.The book begins with four chapters that review the potential applications, possible advantages, and phylogeny of enzybiotics. Next, the book explores:A new approach to controlling infections using Gram-negative bacteriaBacteriophage holins and their membrane-disrupting activityAnti-staphylococcal lytic enzymesMembrane-targeted enzybioticsDesign of phage cocktails for therapy from a host-range point of viewNovel methods to identify new enzybioticsGenetically modified phages that deliver suicidal genes to target bacteriaThe authors, all active enzybiotics researchers, offer a variety of perspectives, the benefit of their own hands-on investigations, as well as a thorough review and analysis of the current literature.As more and more bacteria become resistant to antibiotics, the development of new disease-fighting agents has become essential. This book demonstrates the full potential of the emerging field of enzybiotics to control infectious diseases. Moreover, it will serve as a springboard for new research and the development of new therapeutics.
Main Description
Enzybiotics, by using enzymes to fight bacteria, offer a novel and promising new way to combat infectious diseases. This book presents the state-of-the-art and therapeutic potential of enzybiotics, with a stress on therapeutic applications. The coverage offers a unique combination of medicinal chemistry, microbiology, genetics, and biochemistry. It also addresses the timely topic of bacterial resistance to antibiotics, and provides readers with a novel angle to study and combat infectious diseases.
Main Description
Enzybiotics is promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry, microbiology, genetics, and biochemistry, this book presents the state of the science in enzybiotics research, fully exploring its emerging therapeutic applications.
Long Description
Presents the latest research and applications for a new, promising approach to fighting infectious diseases Enzybiotics is a promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry, microbiology, genetics, and biochemistry, this book presents the state of the science in enzybiotics research, fully exploring its emerging therapeutic applications. The book begins with four chapters that review the potential applications, possible advantages, and phylogeny of enzybiotics. Next, the book explores: A new approach to controlling infections using Gram-negative bacteria Bacteriophage holins and their membrane-disrupting activity Anti-staphylococcal lytic enzymes Membrane-targeted enzybiotics Design of phage cocktails for therapy from a host-range point of view Novel methods to identify new enzybiotics Genetically modified phages that deliver suicidal genes to target bacteria The authors, all active enzybiotics researchers, offer a variety of perspectives, the benefit of their own hands-on investigations, as well as a thorough review and analysis of the current literature. As more and more bacteria become resistant to antibiotics, the development of new disease-fighting agents has become essential. This book demonstrates the full potential of the emerging field of enzybiotics to control infectious diseases. Moreover, it will serve as a springboard for new research and the development of new therapeutics.
Main Description
This book focuses on the state-of-the-art for enzybiotics. It covers the different aspects concerning the knowledge of phages, their lytic enzymes, as well as the use of enzybiotics against fungi; both having possibilities of use in therapy. The different topics are arranged in chapters written by specialists in the different fields.
Bowker Data Service Summary
Enzybiotics, by using enzymes to fight bacteria, offer a novel & promising new way to combat infectious diseases. This book discusses the therapeutic potential of enzybiotics, with a stress on therapeutic applications. The coverage offers a unique combination of medicinal chemistry, microbiology, genetics, & biochemistry.
Table of Contents
Prefacep. vii
Contributorsp. ix
Enzybiotics and Their Potential Applications in Medicinep. 1
Advantages and Disadvantages in the Use of Antibiotics Or Phages As Therapeutic Agentsp. 27
Enzybiotics as Selective Killers of Target Bacteriap. 59
Phylogeny of Enzybioticsp. 75
Bacteriophage Lysins: The Ultimate Enzybioticp. 107
Bacteriophage Holins and their Membrane-Disrupting Activityp. 123
Anti-Staphylococcal Lytic Enzymesp. 149
Membrane-Trageted Enzybioticsp. 173
Design of Phage Cocktails For Therapy From a Host Range Point of Veiwp. 199
Identifying Phage Lytic Enzymes: Past, Present, and Futurep. 219
Use of Genetically Modified Phages to Deliver Suicidal Genes to target Bacteriap. 253
Concluding Remarks: The Future of Enzybioticsp. 269
Indexp. 279
Table of Contents provided by Ingram. All Rights Reserved.

This information is provided by a service that aggregates data from review sources and other sources that are often consulted by libraries, and readers. The University does not edit this information and merely includes it as a convenience for users. It does not warrant that reviews are accurate. As with any review users should approach reviews critically and where deemed necessary should consult multiple review sources. Any concerns or questions about particular reviews should be directed to the reviewer and/or publisher.

  link to old catalogue

Report a problem