Pharmaceutical applications of Raman spectroscopy /
edited by Slobodan Šašić.
Hoboken, N.J. : Wiley-Interscience, c2008.
xiv, 264 p., [4] p. of plates : ill. (some col.) ; 25 cm.
0813810132 (cloth), 9780813810133 (cloth)
More Details
added author
Hoboken, N.J. : Wiley-Interscience, c2008.
0813810132 (cloth)
9780813810133 (cloth)
contents note
Introduction to Raman spectroscopy / Yukihiro Ozaki and Slobodan Šašić -- Quantitative analysis of solid dosage formulations by Raman spectroscopy / Steven J.E. Bell -- Surface enhanced resonance Raman scattering / W. Ewen Smith -- Raman spectroscopy for identifying polymorphs / Fred Laplant and Anne De Paepe -- Raman spectroscopy for monitoring real-time processes in the pharmaceutical industry / Kevin L. Davis, Mark S. Kemper and Ian R. Lewis -- Raman chemical imaging of solid dosage formulations / Slobodan Šašić -- In vivo Raman confocal microspectroscopy of skin / Andre van der Pol, William M. Riggs and Peter J. Caspers -- Raman microspectroscopy and imaging of active pharmaceutical ingredients in cells / Jian Ling.
catalogue key
Includes bibliographical references and index.
A Look Inside
This item was reviewed in:
SciTech Book News, September 2008
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Bowker Data Service Summary
Carefully organised with a emphasis on industry issues, this book provides the basic theory of the Raman effect and instrumentation, and addresses a wide range of pharmaceutical applications.
Main Description
Raman spectroscopy has advanced in recent years with increasing use both in industry and academia. This is due largely to steady improvements in instrumentation, decreasing cost, and the availability of chemometrics to assist in the analysis of data. Pharmaceutical applications of Raman spectroscopy have developed similarly and this book will focus on those applications. Carefully organized with an emphasis on industry issues, Pharmaceutical Applications of Raman Spectroscopy, provides the basic theory of Raman effect and instrumentation, and then addresses a wide range of pharmaceutical applications. Current applications that are routinely used as well as those with promising potential are covered. Applications cover a broad range from discovery to manufacturing in the pharmaceutical industry and include identifying polymorphs, monitoring real-time processes, imaging solid dosage formulations, imaging active pharmaceutical ingredients in cells, and diagnostics.
Table of Contents
Introduction to Raman Spectroscopy
Histor of Raman Spectrodcopy
The Principle of Raman Spectroscopy
An Example of Simpel Raman Spectrum: Raman Spectrum of Water
Characteristics of Raman Spectroscopy
The Classic Theory fo Raman Effect
The Quantum Theory of Raman Scattering
Ctross Section
Relevance to Pharmaceuticals
Resonance Raman Effect
Instrumentation for Raman Spectroscopy
Quantitative Analysis of Solid Dosage Formulations by Raman Spectroscopy
Quantitative Analysis
Instrumental Parameters
Experimental Considerations
Nonstandard Samples
Surface Enhanced Resonance Raman Scatttering
The Exper4imental Setup
Examples of SERS/SERRS Assays
Raman Spectroscopy for Identifying Polymorphs
Introduction of Polymorphism
Instrumental Methods of Polymorph Characterization
Polymorph Screening
Process Control
Polymorph Quantitation
Calibration Set and Sample Preparation
Intellectual Property
Raman Spectroscopy for Monitoring Real-time Processes in the Pharmaceutical Industry
A Brief History of Raman Spectroscopy
Basic Theory of Raman Spectroscopy
General Instrumentation for Raman Spectroscopy
The Choice-Dispersive or FT?
Process Analysis and PAT
Why Choose Raman as a PAT Tool? The Need for Raman
Data Analysis
Raman Chemical Imaging of Solid Dosage Formulations
Methods for Chemcial Imaging
Data Analysis
In vivo Raman Confocal Microspectroscopy of Skin
Summary and Discussion
Raman Microspectrscopy and Imgaging of Active Pharmaceutical Ingredients in Cells
Current Appraoches to Drug Imaging
Raman Spectroscopy and Raman Imaging
Raman Microspectroscopy and Imaging for Drug Research
Raman Intensity, Fluorescence Background, and SNR
Techniques to Improve SNR in Raman Imaging
Enhanced Raman Images with Postprocessing
Raman Imaging of Intracellular Distribution of Paclitaxel in Living Cells
Raman Imaging of Intracellular Distribution of Sulindac Sulfide in Fixed Cells
Conclusions and Future Outlook
Table of Contents provided by Publisher. All Rights Reserved.

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