Catalogue


Advances in Antiviral Drug Design [electronic resource].
imprint
Elsevier Science Ltd 2007.
ISBN
0444521739, 9780444521736
format(s)
Book
Subjects
genre index term
More Details
imprint
Elsevier Science Ltd 2007.
isbn
0444521739
9780444521736
contents note
Status presens of antiviral drugs and strategies, Part I: DNA viruses and retroviruses -- Status presens of antiviral drugs and strategies, Part II: RNA viruses (except retroviruses) -- Methylenecyclopropane analogues of nucleosides as anti-herpes agents -- Synthesis and antiviral evaluation of broad spectrum orally active analogs of cidofovir and other acyclic nucleoside phosphonates -- CCR5 antagonists for the treatment of HIV infection and AIDS -- The medicinal chemistry of the DATA and DAPY series of HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs).
abstract
Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use.
catalogue key
6262023
 
Electronic reproduction. Amsterdam : Elsevier Science & Technology, 2007. Mode of access: World Wide Web. System requirements: Web browser. Title from title screen (viewed on July 25, 2007). Access may be restricted to users at subscribing institutions.
A Look Inside
Summaries
Main Description
Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use.
Table of Contents
List of Contributorsp. vii
Prefacep. ix
Status Presens of Antiviral Drugs and Strategies: Part I: DNA Viruses and Retrovirusesp. 1
Status Presens of Antiviral Drugs and Strategies: Part II: RNA Viruses (Except Retroviruses)p. 59
Methylenecyclopropane Analogues of Nucleosides as Anti-Herpes Agentsp. 113
Synthesis and Antiviral Evaluation of Broad Spectrum, Orally Active Analogs of Cidofovir and Other Acyclic Nucleoside Phosphonatesp. 167
CCR5 Antagonists for the Treatment of HIV Infection and Aidsp. 185
The Medicinal Chemistry of the Data and Dapy Series of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIS)p. 213
Indexp. 243
Table of Contents provided by Ingram. All Rights Reserved.

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