Catalogue


Essentials of pathophysiology for pharmacy /
Martin M. Zdanowicz.
imprint
Boca Raton : CRC Press, c2003.
description
228 p. : il. ; 24 cm.
ISBN
1587160366
format(s)
Book
Holdings
More Details
imprint
Boca Raton : CRC Press, c2003.
isbn
1587160366
catalogue key
5063146
 
Includes bibliogrlaphical references.
A Look Inside
Reviews
This item was reviewed in:
Doody's Reviews, November 2002
To find out how to look for other reviews, please see our guides to finding book reviews in the Sciences or Social Sciences and Humanities.
Summaries
Main Description
This textbook stresses topics in pathophysiology that are most pertinent to students pursuing degrees in pharmacy. It is designed to provide students with a clear rationale for the use of a specific drug in selected disease states. The text is also supplemented with "Key Term" boxes that provide clear definitions of medical and physiologic terms. Drug boxes throughout the text provide a concise synopsis of selected drugs associated with the particular disease state, including generic and class names, routes of administration, major side effects and contradictions. Numerous tables and charts are also offered to expand upon and summarize key elements as are questions, study objectives, and diagnostic tools boxes are included.
Back Cover Copy
Presenting all the information your students need in an accessible layout, Essentials of Pathophysiology for Pharmacy will give students a practical understanding of the pathophysiologic basis of selected diseases while providing a rationale for subsequent drug therapy.
Table of Contents
Cellular injury
Study objectivesp. 1
Introductionp. 3
Cellular adaptationp. 3
Cellular injuryp. 4
Free radical injuryp. 5
Hypoxic cell injuryp. 5
Manifestations of cellular injuryp. 6
Cell deathp. 6
Apoptosisp. 6
Necrotic cell deathp. 7
Tissue repairp. 7
Types of tissue repairp. 8
Steps in tissue (wound) repairp. 8
Cancer
Study objectivesp. 11
Introductionp. 13
Cancer terminologyp. 13
Theories of oncogenesisp. 14
Abnormalities of tumor suppressor/inducer genesp. 14
Mutation of DNAp. 15
Hereditaryp. 15
Manifestations of cancerp. 15
Tumor stagingp. 16
Cancer detectionp. 16
Tumor cell markersp. 16
Visualizationp. 18
Biopsyp. 18
Rationale for therapyp. 18
Treatment of cancerp. 18
Surgical removalp. 18
Chemotherapyp. 18
Hormonal therapyp. 18
Radiation therapyp. 19
Immune-based therapiesp. 19
Disorders of hemostasis and coagulation
Study objectivesp. 21
Introductionp. 23
Steps in hemostasisp. 23
Vascular spasmp. 23
Formation of platelet plugp. 23
Activation of blood coagulation cascadesp. 24
Intrinsic pathwayp. 24
Extrinsic pathwayp. 25
Formation of fibrin clotp. 25
Clot retractionp. 25
Fibrinolysis (clot dissolution)p. 25
Conditions leading to decreased coagulationp. 25
Genetic defectsp. 25
Hemophiliap. 25
von Willebrand's diseasep. 26
Autoimmune defectsp. 27
Idiopathic thrombocytopenia purpurap. 27
Thrombocytopeniap. 27
Acquired deficienciesp. 27
Vitamin K deficiencyp. 27
Liver diseasep. 28
Drug-induced alterations in hemostasis and coagulationp. 28
Conditions leading to increased blood coagulationp. 28
Alterations in hematologic function and oxygen transport
Study objectivesp. 29
Introductionp. 31
Hematopoiesisp. 31
Anemiap. 33
General manifestations of anemiap. 33
Types of anemiap. 33
Hemolytic anemiap. 33
Blood loss anemiap. 34
Iron-deficiency anemiap. 34
Cobalamin-deficiency or folate-deficiency anemiap. 34
Inherited anemiap. 34
Manifestations of thalassemiap. 36
Aplastic anemiap. 36
Polycythemiap. 37
Manifestationsp. 37
Treatmentp. 38
Immune response and inflammation
Study objectivesp. 39
Introductionp. 41
Components of the immune systemp. 41
Antigensp. 41
Major histocompatability complex (MHC)p. 41
MHC Ip. 42
MHC IIp. 42
Monocytes and macrophagesp. 42
Lymphocytesp. 42
T lymphocytes (T cells)p. 43
B lymphocytes (B cells)p. 43
Antibodiesp. 44
Natural killer cellsp. 46
Cytokinesp. 46
Complement proteinsp. 46
The inflammatory reactionp. 47
Hypersensitivity reactionsp. 48
Acquired immune deficiency syndrome (AIDS)
Study objectivesp. 51
Introductionp. 53
HIV structurep. 53
Stages in an HIV infectionp. 54
Epidemiology of HIV infectionp. 55
Laboratory diagnosis of HIVp. 56
Rationale for treatment of HIVp. 56
Treatment of HIVp. 56
Diseases of the vascular system
Study objectivesp. 59
Introductionp. 61
Arterial diseasep. 61
Atherosclerosisp. 61
Manifestations of atherosclerosisp. 62
Aneurysmp. 64
Clinical manifestations of aneurysmp. 65
Treatment of aneurysmsp. 66
Vasospastic conditionsp. 66
Arterial inflammationp. 66
Disease of the veinsp. 66
Varicose veinsp. 66
Chronic venous insufficiencyp. 67
Venous thrombusp. 68
Treatment and prevention of venous thrombusp. 68
Embolismp. 68
Anticoagulant and thrombolytic drug therapyp. 69
Alterations in blood pressure
Study objectivesp. 71
Introductionp. 73
Primary or essential hypertensionp. 73
Manifestations of essential hypertensionp. 74
Rationale for treatment of essential hypertensionp. 75
Treatmentp. 75
Secondary hypertensionp. 76
Malignant hypertensionp. 76
Hypotensionp. 76
Manifestationsp. 77
Treatmentp. 77
Diseases of the heart
Study objectivesp. 79
Introductionp. 81
Disorders of the pericardiump. 81
Acute pericarditisp. 81
Manifestationsp. 81
Pericardial effusionp. 81
Manifestationsp. 82
Constrictive (chronic) carditisp. 82
Rationale for treatment of pericarditisp. 83
Diseases of the myocardiump. 83
Myocarditisp. 83
Manifestationsp. 83
Cardiomyopathiesp. 83
Types of cardiomyopathyp. 83
Rationale for treatment of cardiomyopathyp. 85
Disorders of the endocardium and heart valvesp. 85
Infectious endocarditisp. 85
Manifestationsp. 86
Treatmentp. 86
Rheumatic heart diseasep. 86
Manifestationsp. 86
Disorders of the heart valvesp. 86
Mitral valve prolapsep. 88
Rationale for treatment of valvular diseasep. 88
Congenital heart defectsp. 89
Patent ductus arteriosusp. 89
Myocardial ischemia
Study objectivesp. 91
Introductionp. 93
Manifestations of myocardial ischemiap. 93
Rationale for treatment of myocardial ischemiap. 94
Treatment of myocardial ischemiap. 94
Nonpharomacologic treatmentp. 94
Pharmacologic treatmentp. 95
Surgical treatmentp. 96
Myocardial infarction
Study objectivesp. 97
Introductionp. 99
Coronary blood flow and myocardial infarctionp. 99
Manifestations of myocardial infarctionp. 99
Complications of myocardial infarctionp. 100
Compensatory mechanisms for myocardial infarctionp. 100
Rationale for therapyp. 101
Treatment for myocardial infarctionp. 101
Heart failure and shock
Study objectivesp. 103
Introductionp. 105
Manifestations of heart failurep. 105
Left heart failurep. 105
Right heart failurep. 106
Systolic failure vs. diastolic failurep. 108
Systolic failurep. 108
Diastolic failurep. 108
Physiologic compensation for heart failurep. 108
Rationale for treatment of heart failurep. 110
Circulatory shockp. 112
Physiologic responses to shockp. 113
Stages of shockp. 113
Complications of shockp. 114
Rationale for therapyp. 114
Treatment of shockp. 115
Abnormalities of cardiac conduction
Study objectivesp. 117
Introductionp. 119
Cardiac conduction systemp. 119
Cardiac action potentialsp. 120
Phases of cardiac muscle cell action potentialp. 120
Phases of action potential for cardiac pacemaker cellsp. 120
Electrocardiographyp. 122
Components of a normal ECGp. 122
Factors that may contribute to the development of a cardiac arrhythmiap. 122
Mechanisms of cardiac arrhythmiap. 122
Ectopic pacemakersp. 122
Reentry impulsesp. 123
Types of arrhythmiap. 124
Sinus node arrhythmiap. 124
Atrial arrhythmiap. 124
Ventricular arrhythmiap. 125
Heart blockp. 126
Diagnosis of arrhythmiap. 127
Rationale for the treatment of cardiac arrhythmiap. 127
Treatment of cardiac arrhythmiap. 128
Pharmacologic treatmentp. 128
Nonpharmacologic treatment of arrhythmiap. 129
Disorders of the respiratory system
Study objectivesp. 131
Introductionp. 133
Respiratory infectionsp. 133
Infections of the upper respiratory tractp. 133
The common coldp. 133
Influenzap. 134
Infections of the lower respiratory tractp. 135
Pneumoniap. 135
Tuberculosisp. 137
Obstructive respiratory disordersp. 139
Restrictive pulmonary disordersp. 144
Respiratory failurep. 149
Abnormalities of the kidney and urinary tract
Study objectivesp. 151
Introductionp. 153
Disorders of the kidneyp. 153
Acute glomerulonephritisp. 154
Rapidly progressing glomerulonephritisp. 154
Chronic glomerulonephritisp. 155
Manifestations of glomerulonephritisp. 155
Treatment of glomerulonephritisp. 156
Urinary tract infectionsp. 156
Manifestationsp. 156
Treatmentp. 156
Renal calculi (kidney stones)p. 156
Manifestationsp. 157
Treatmentp. 157
Renal tumorsp. 157
Manifestationsp. 157
Treatmentp. 158
Polycystic kidney diseasep. 158
Manifestationsp. 158
Treatmentp. 158
Renal failurep. 158
Acute renal failurep. 159
Chronic renal failurep. 160
Manifestationsp. 160
Disorders of the bladder and uretherap. 162
Urine refluxp. 162
Neurogenic bladderp. 163
Gastrointestinal disorders
Study objectivesp. 165
Introductionp. 167
Abnormalities of the esophagusp. 167
Dysphagiap. 167
Achalasiap. 168
Esophageal diverticulump. 168
Gastroesophageal reflux diseasep. 168
Manifestationsp. 168
Treatmentp. 169
Disorders of the stomachp. 169
Gastritisp. 169
Acute gastritisp. 169
Chronic gastritisp. 169
Peptic ulcersp. 170
Manifestations of peptic ulcer diseasep. 170
Treatment of peptic ulcer diseasep. 171
Disorders of the intestinesp. 171
Irritable bowel syndromep. 171
Inflammatory bowel diseasep. 171
Crohn's diseasep. 172
Ulcerative colitisp. 173
Disorders of the gall bladderp. 174
Gallstone formation (cholelithiasis)p. 174
Cholecystitisp. 174
Diverticular diseasep. 175
Manifestations of diverticular diseasep. 175
Treatment of diverticular diseasep. 176
Colorectal cancerp. 176
Manifestations of colorectal cancerp. 176
Disease of the liver and exocrine pancreas
Study objectivesp. 177
Introductionp. 179
Viral hepatitisp. 179
Epidemiologyp. 180
Manifestations of viral hepatitisp. 180
Possible complications of hepatitisp. 181
Treatment of hepatitisp. 182
Cirrhosisp. 182
Stages of alcoholic liver diseasep. 182
Manifestations of alcoholic cirrhosisp. 183
Treatment of cirrhosisp. 184
Liver cancerp. 184
Disorders of the pancreas--Pancreatitisp. 184
Manifestationsp. 184
Treatmentp. 185
Endocrine disorders
Study objectivesp. 187
Introductionp. 189
Abnormalities of the hypothalamus/pituitary glandsp. 189
Hypopituitarismp. 190
Disorders of the anterior pituitary glandp. 191
Alterations of growth hormone secretionp. 191
Growth hormone hyposecretionp. 191
Growth hormone hypersecretion--Gigantism and acromegalyp. 192
Disorders of the posterior pituitaryp. 193
Syndrome of inappropriate ADH (SIADH)p. 193
Diabetes insipidusp. 193
Alteration of thyroid functionp. 194
Hypothyroidismp. 194
Manifestationsp. 194
Myxedemap. 195
Treatmentp. 195
Hyperthyroidismp. 195
Grave's diseasep. 195
Disorders of the adrenal glandsp. 196
Hyposecretion of adrenal hormonesp. 196
Congenital adrenal hypoplasia (CAH)p. 196
Addison's diseasep. 197
Cushing's diseasep. 198
Disorders of the adrenal medullap. 199
Pheochromocytomap. 199
Diabetes mellitus
Study objectivesp. 201
Introductionp. 203
Endocrine pancreasp. 203
Types of diabetes mellitusp. 204
Type I diabetes (insulin-dependent diabetes)p. 204
Manifestationsp. 204
Treatmentp. 204
Type II diabetes mellitus (non-insulin-dependent diabetes)p. 206
Manifestationsp. 207
Treatmentp. 207
Long-term complications of diabetes mellitusp. 208
Gestational diabetesp. 210
Referencesp. 211
Selected bibliographyp. 213
Indexp. 215
Table of Contents provided by Syndetics. All Rights Reserved.

This information is provided by a service that aggregates data from review sources and other sources that are often consulted by libraries, and readers. The University does not edit this information and merely includes it as a convenience for users. It does not warrant that reviews are accurate. As with any review users should approach reviews critically and where deemed necessary should consult multiple review sources. Any concerns or questions about particular reviews should be directed to the reviewer and/or publisher.

  link to old catalogue

Report a problem