Catalogue


Surfactants and polymers in drug delivery /
Martin Malmsten.
imprint
New York : Marcel Dekker, c2002.
description
vii, 348 p. : ill.
ISBN
0824708040 (alk. paper)
format(s)
Book
Holdings
More Details
imprint
New York : Marcel Dekker, c2002.
isbn
0824708040 (alk. paper)
catalogue key
4724482
 
Includes bibliographical references and index.
A Look Inside
About the Author
Author Affiliation
Martin Malmsten is Managing Director of the Institute for Surface Chemistry and Professor at the Royal Institute of Technology, Stockholm, Sweden.
Reviews
This item was reviewed in:
SciTech Book News, December 2002
To find out how to look for other reviews, please see our guides to finding book reviews in the Sciences or Social Sciences and Humanities.
Summaries
Main Description
This indispensable reference features the latest findings surrounding the physicochemical aspects of surfactant and polymer systems to facilitate the design and understanding of novel and advanced drug delivery formulations-highlighting the basics of surfactant and polymer surface activity and self-assembly, the various types of structures formed by such compounds, and how they may be used in drug delivery. Surfactants and Polymers in Drug Delivery discusses solubilization of drugs in micellar systems liquid crystalline phases formed by PEO-PPO-PEO block copolymers and other copolymers and surfactants triggered drug-release from liposome formulations microemulsions formed by ionic and nonionic surfactants microemulsions in oral and topical administration emulsions in parenteral, oral, and dermal drug delivery gels formed by polysaccharides, block copolymers, and polymer-surfactant mixtures chemically cross-linked gels responsive polymer systems in drug delivery experimental techniques for studying drug delivery systems drying of aqueous protein solutions, polymeric two-phase systems, emulsions, and liposomes bioadhesion With nearly 500 references, tables and figures, Surfactants and Polymers in Drug Delivery will benefit surface, pharmaceutical, colloid, polymer, and medicinal chemists; chemical, formulation, and application engineers; and pharmacists; and upper-level undergraduate and graduate students in these disciplines.
Main Description
This reference features the latest findings surrounding the physicochemical aspects of surfactant and polymer systems to facilitate the design and understanding of novel and advanced drug delivery formulations. It covers the basics of surfactant and polymer surface activity and self-assembly, the various types of structures formed by such compounds, and how they may be used in drug delivery. It also discusses solubilization of drugs in micellar systems, liquid crystalline phases formed by PEO-PPO-PEO block copolymers and other copolymers and surfactants, triggered drug-release from liposome formulations, microemulsions formed by ionic and nonionic surfactants, and much more.
Bowker Data Service Summary
This volume features findings surrounding the physiochemical aspects of surfactant and polymer systems. It highlights the basics of surfactant and polymer surface activity and self-assembly, the various types of structures formed by such compounds and how they may be used in drug delivery.
Table of Contents
Prefacep. iii
Introductionp. 1
Introduction to Surfactantsp. 2
Introduction to Polymersp. 9
Surface Activity of Drugsp. 10
Introduction to Drug Deliveryp. 15
Bibliographyp. 17
Micellesp. 19
Structure and Dynamics of Micellar Systemsp. 19
Block Copolymer Micellesp. 27
Characterization of Micellar Systemsp. 36
Micellar Systems in Drug Deliveryp. 40
Bibliographyp. 49
Liquid Crystalline Phasesp. 51
Association Structures and Packingp. 51
Phase Diagramsp. 53
Association in Nonionic Surfactant Systemsp. 56
Association in Ionic Surfactant Systemsp. 60
Cubic Phasesp. 62
Liquid Crystalline Phases Formed by PEO-PPO-PEO Block Copolymersp. 63
Characterization of Liquid Crystalline Phasesp. 68
Liquid Crystalline Phases as Drug Delivery Systemsp. 70
Liquid Crystalline Phases in Drug Delivery Applicationsp. 80
Bibliographyp. 86
Liposomesp. 87
Preparation and Properties of Liposome Systemsp. 87
Solubilization and Release from Liposomesp. 94
Methods for Investigating Liposome Systemsp. 97
Liposomes in Drug Deliveryp. 102
Other Types of Dispersed Liquid Crystalline Phasesp. 128
Bibliographyp. 131
Microemulsionsp. 133
Basics of Microemulsionsp. 133
Characterization of Microemulsionsp. 141
Drug Release from Microemulsionsp. 144
Microemulsions in Drug Deliveryp. 146
Bibliographyp. 159
Emulsionsp. 161
Formation of Emulsionsp. 161
Structure of Emulsionsp. 167
Phase Inversion of Emulsionsp. 167
Rheology of Emulsionsp. 173
Destabilization of Emulsionsp. 176
Multiple Emulsionsp. 182
Emulsions in Drug Deliveryp. 183
Emulsions as Precursors for SLNp. 192
Bibliographyp. 199
Aerosols, Bubbles, and Foamsp. 201
Aerosolsp. 201
Bubbles and Foamsp. 203
Pharmaceutical Applications of Aerosolsp. 207
Pharmaceutical Applications of Bubbles and Foamsp. 208
Bibliographyp. 213
Polymer Solutions and Gelsp. 215
Polymer Solutionsp. 215
Polymer-Surfactant Interactionsp. 222
Polymer Gelsp. 226
Characterization of Polymer Solutions and Gelsp. 238
Responsive Polymer Systemsp. 242
Polymer Solutions and Gels in Drug Deliveryp. 245
Bibliographyp. 259
Polymer Particlesp. 261
Interaction Between Particlesp. 261
Interaction Between Particles and Surfacesp. 269
Methods for Studying Polymer Particle Systemsp. 270
Polymer Particles in Drug Deliveryp. 279
Bioadhesionp. 284
Oral Vaccinesp. 288
Bibliographyp. 290
Degradation of Surfactants and Polymers in Drug Deliveryp. 293
Biodegradation of Polymersp. 293
Biodegradation of Phospholipidsp. 312
Bibliographyp. 316
Drying of Formulations Containing Surfactants and Polymersp. 319
Spray-Dryingp. 320
Freeze-Dryingp. 326
Drying of Self-Assembled Structuresp. 332
Bibliographyp. 335
Indexp. 337
Table of Contents provided by Syndetics. All Rights Reserved.

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