Catalogue


Negative symptom and cognitive deficit treatment response in schizophrenia /
edited by Richard S.E. Keefe, Joseph P. McEvoy.
edition
1st ed.
imprint
Washington, DC : American Psychiatric Press, c2001.
description
xiv, 201 p. : ill. ; 24 cm.
ISBN
0880487852 (alk. paper)
format(s)
Book
Holdings
More Details
imprint
Washington, DC : American Psychiatric Press, c2001.
isbn
0880487852 (alk. paper)
catalogue key
4660316
 
Includes bibliographical references and index.
A Look Inside
Excerpts
Flap Copy
For the first time in a single volume, distinguished experts address the complex issues-issues rarely confronted in empirical studies of patients with schizophrenia-and controversial research surrounding the assessment of negative symptoms and cognitive deficits in patients with schizophrenia. Despite recent advances in our understanding of schizophrenia, still notably absent is consensus in assessing negative symptom treatment response. What is the most effective assessment method? What constitutes an adequate response? Which medication yields the best results? What are the indications for use of this medication? Which instrument best measures negative symptom treatment response? By clarifying the issues surrounding such complex questions, these detailed chapters bring clinicians and researchers alike closer to consensus than ever before. Negative Symptom and Cognitive Deficit Treatment Response in Schizophrenia also details other key topics, including the effects of treatment on social functioning and subjective experience of "quality of life," the importance of neurocognitive dysfunction, guidelines for assessing neurocognitive treatment response, the latest research on the neurobiology of negative symptoms, and ways to distinguish negative symptoms from deficit symptoms and effectively treat them. Highlighted by patient vignettes, this in-depth guide will be welcomed by all clinicians who treat patients with schizophrenia and want to know and document whether their interventions ameliorate negative symptoms and cognitive dysfunction, and by all researchers who study schizophrenia, particularly those interested in clinical issues and treatment studies.
Reviews
Review Quotes
"This book provides much information about one of the most important current issues in the treatment of schizophrenia and it covers both pharmaceutical and psychosocial aspects of treatment."- Peter E. Liddle, British Journal of Psychiatry , March 2002
"This book comprehensively covers one of the most important topics in psychiatry. As a major cause of functional disability, the treatment of negative and cognitive symptoms is a matter of the highest priority. Assembling a collection of the most experienced researchers in the field, this book covers all of the important topics in a clearly written and thorough manner. The newest developments in research and theory are interspersed with informative clinical observations, leading to a highly readable collection of chapters of an optimal length."- Philip D. Harvey, Ph.D., Professor of Psychiatry, Mount Sinai School of Medicine, New York, New York
For trainee, trainer, and researcher, there is much to be gained from reading this book.
"For trainee, trainer, and researcher, there is much to be gained from reading this book."- Psychological Medicine , 2003
Negative Symptom and Cognitive Deficit Treatment Response in Schizophrenia provides an excellent overview of the state of the science of negative symptoms and neurocognitive deficits in schizophrenia.
" Negative Symptom and Cognitive Deficit Treatment Response in Schizophrenia provides an excellent overview of the state of the science of negative symptoms and neurocognitive deficits in schizophrenia."- Mark R. Munetz M.D., Psychiatric Services , November 2002
"The development of effective treatments for negative symptoms and cognitive impairments remains the critical challenge facing schizophrenia therapeutics. This book provides the clinician with an accessible and comprehensive overview of the assessment issues, approaches, and tools that should enhance the everyday care of patients with schizophrenia."- Jim Gold, Ph.D., Maryland Psychiatric Research Center, University of Maryland, Baltimore, Baltimore, Maryland
To find out how to look for other reviews, please see our guides to finding book reviews in the Sciences or Social Sciences and Humanities.
Summaries
Main Description
For the first time in a single volume, distinguished experts address the complex issues-issues rarely confronted in empirical studies of patients with schizophrenia-and controversial research surrounding the assessment of negative symptoms and cognitive deficits in patients with schizophrenia.
Main Description
For the first time in a single volume, distinguished experts address the complex issues-issues rarely confronted in empirical studies of patients with schizophrenia-and controversial research surrounding the assessment of negative symptoms and cognitive deficits in patients with schizophrenia. Despite recent advances in our understanding of schizophrenia, still notably absent is consensus in assessing negative symptom treatment response. What is the most effective assessment method-given the varying methodologies and contradictory results to date? What constitutes an adequate response? Which medication-none is specifically indicated and licensed for negative symptom treatment-yields the best results? What are the indications for use of this medication? Which instrument best measures negative symptom treatment response (eight rating scales are analyzed here)? Reaching consensus among clinicians and researchers alike is even more difficult because assessment is often thwarted by extrapyramidal side effects of medications, similarities to depressive symptoms, and secondary effects of psychotic experiences. In addition to clarifying these pressing issues, Negative Symptom and Cognitive Deficit Treatment Response in Schizophrenia also discusses The importance of measuring the experience of emotion versus the more traditional objectively measured symptoms in patients with schizophrenia, and how deficits in emotional experience may resist treatment-even in treatment-responsive patients. The family as an often overlooked source of information about negative symptom improvement or worsening, and the impact of negative symptoms on patients' relatives. How treatment affects social functioning and subjective experience of "quality of life," and the importance of neurocognitive dysfunction in the social deficits of schizophrenia, which often persist despite significant amelioration of other symptoms. Specific guidelines for assessing neurocognitive treatment response. Cognitive enhancement is a major factor in improving the quality of patients' lives. The latest research on the neurobiology of negative symptoms, including the role of various neurotransmitter systems and brain regions in mediating negative symptom pathology. Also discussed is single vs. multiple pathophysiological processes and single treatment modality vs. distinct treatments for different aspects of negative symptoms. How to distinguish "pure" negative symptoms from deficit symptoms (i.e., those that persist for at least 1 year and are not secondary to factors such as depression, medication side effects, anxiety, delusions, and hallucinations), and which treatment is indicated for each. Highlighted by patient vignettes, this in-depth guide will be welcomed by all clinicians who treat patients with schizophrenia and want to know and document whether their interventions ameliorate negative symptoms and cognitive dysfunction, and by all researchers who study schizophrenia, particularly those interested in clinical issues and treatment studies.
Table of Contents
Contributors
Introduction
Evaluating Negative Symptom Treatment Efficacyp. 1
Issues in the Assessment of Negative Symptom Treatment Responsep. 19
Social Functioning and Its Relationship to Cognitive Deficits Over the Course of Schizophreniap. 33
Evaluation of Negative Symptoms in Short-Term Pharmacological Trialsp. 69
Negative Symptoms and the Assessment of Neurocognitive Treatment Responsep. 85
Negative Symptoms and the Experience of Emotionp. 111
The Family Perspective in the Assessment of Negative Symptom Treatment Efficacyp. 139
Regulatory Aspects of Drug Treatment for Negative Symptomsp. 153
The Biology and Pathophysiology of Negative Symptomsp. 163
Indexp. 187
Table of Contents provided by Blackwell. All Rights Reserved.

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