Catalogue


The osteoporosis primer /
edited by Janet E. Henderson and David Goltzman.
imprint
Cambridge, UK ; New York : Cambridge University Press, 2000.
description
xiv, 372 p. : ill.
ISBN
0521644461 (pbk.)
format(s)
Book
Holdings
Subjects
subject
More Details
imprint
Cambridge, UK ; New York : Cambridge University Press, 2000.
isbn
0521644461 (pbk.)
catalogue key
3868114
 
Includes bibliographical references and index.
A Look Inside
Reviews
Review Quotes
"The chapters in each section are written by acknowledged experts, and in general the content and treatment are excellent. Each chapter therefore represents a useful component in a collection of reviews...for those with complete knowledge of the field who wish to extend their breadth of interest. To this end, it is a very useful contribution to the literature." New England Journal of Medicine
'This is a concise yet comprehensive synopsis of bone developments and skeletal homeostasis.' Aslib Book Guide
'This is a concise yet comprehensive synopsis of bone developments and skeletal homeostasis.'Aslib Book Guide
‘This is a concise yet comprehensive synopsis of bone developments and skeletal homeostasis.’Aslib Book Guide
"..the book succeeds as an introductory text on metabolic bone disease and provides insight into the complexity of the subject without becoming overwhelming." Gerontology
'I really enjoyed tying together the cell biology and the basis of the current treatments and potential therapeutic interventions. I found that I knew a lot more about bone cell physiology, bone turnover and cell signalling by the end of the section. ... The book succeeds as an introductory text on metabolic bone disease and provides insight into the complexity of the subject without becoming overwhelming.' Gerontology
"...it is a very thorough text with outstanding references for each chapter. The chapters are written by scientists and clinicians who are well known in their fields...a thorough basic-science review, not only of osteoporosis but of metabolic bone disease in general. It is extremely up-to-date, with numerous references, and it will help to enhance the reader's knowledge in the very fast-moving field of osteoporosis." The Journal of Bone & Joint Surgery
‘I really enjoyed tying together the cell biology and the basis of the current treatments and potential therapeutic interventions. I found that I knew a lot more about bone cell physiology, bone turnover and cell signalling by the end of the section. … The book succeeds as an introductory text on metabolic bone disease and provides insight into the complexity of the subject without becoming overwhelming.’Gerontology
"a good treattise on osteoporosis. It is also very well referenced for those who desire further information...should be well worth the purchase" Forum Jan/Feb 2002
"...a useful, easily readable text, on a topic of increasing interest." Journal of Endocrine Genetics
‘A clearly written and updated text … on a topic of increasing interest.’Journal of Pediatric Endocrinology and Metabolism
"A comprehensive summary of bone development, skeletal homeostasis and disorders of bone metabolism...This primer is a useful and concise introduction to the manner in which osteoporosis relates clinically to its molecular biochemical basis." Doody's Review Service ®
'A clearly written and updated text ... on a topic of increasing interest.' Journal of Pediatric Endocrinology and Metabolism
'A clearly written and updated text ... on a topic of increasing interest.'Journal of Pediatric Endocrinology and Metabolism
This item was reviewed in:
Doody's Reviews, January 2001
To find out how to look for other reviews, please see our guides to finding book reviews in the Sciences or Social Sciences and Humanities.
Summaries
Main Description
Osteoporosis is one of the leading causes of morbidity and mortality amongst the elderly. The rationale for The Osteoporosis Primer is to provide an introductory text that relates the clinical presentation of osteoporosis to its molecular biochemical basis. The text has been organised into four sections that deal with the molecular/cellular components of bone, the development of peak bone mass, the pathophysiology of aging bone and, finally, how all of these relate to the prevention, diagnosis and treatment of osteoporosis. The international team of authors includes many leading clinicians and scientists who have provided the reader with a concise, yet comprehensive, synopsis of bone development and skeletal homeostasis. This will be an essential introduction for individuals working on osteoporosis including students and doctors considering a career related to metabolic bone disease, physicians in general practice, geriatricians, rheumatologists, and endocrinologists.
Description for Bookstore
Osteoporosis is one of the leading causes of morbidity and mortality amongst the elderly. The rationale for The Osteoporosis Primer is to provide an introductory text that relates the clinical presentation of osteoporosis to its molecular biochemical basis, and reviews therapeutic options. This book provides an essential introduction for individuals working on metabolic bone disease, including students and doctors considering a career related to metabolic bone disease, physicians in general practice, geriatricians, rheumatologists, and endocrinologists.
Bowker Data Service Summary
The rationale for this text is to provide an introductory text that relates the clinical presentation of osteoporosis to its molecular biochemical basis. It provides the reader with a synopsis of bone development and skeletal homeostasis.
Description for Bookstore
Osteoporosis is one of the leading causes of morbidity and mortality amongst the elderly. The Osteoporosis Primer provides an excellent introduction that relates the clinical presentation of osteoporosis to its molecular biochemical basis, and reviews therapeutic options. It will be an essential read for all those working on metabolic bone disease.
Main Description
Osteoporosis is one of the leading causes of morbidity and mortality among the elderly. The rationale for The Osteoporosis Primer is to provide an introductory text that relates the clinical presentation of osteoporosis to its molecular biochemical basis. The text has been organized into four sections that deal with the molecular/cellular components of bone, the development of peak bone mass, the pathophysiology of aging bone and finally, how all of these relate to the prevention, diagnosis, and treatment of osteoporosis. The international team of authors includes many leading clinicians and scientists who have provided the reader with a concise, yet comprehensive, synopsis of bone development and skeletal homeostasis. This book will be an essential introduction for individuals working on osteoporosis, including students and doctors considering a career related to metabolic bone disease, general practitioners, geriatricians, rheumatologists, and endocrinologists.
Table of Contents
Preface
Molecular and Cellular Environment of Bone
Endochondral bone formation and development in the axial and appendicular skeletaon
The role of osteoblasts
Osteoclasts: characteristics and regulation of formation and activity
Bone matrix proteins
Local regulators of bone turnover
The PTH/PTHrP system and calcium homeostasis
Vitamin D metabolism
Sodium-dependent phosphate transport in kidney, bone and intestine
Determinants of Peak Bone Mass
Molecular genetic analysis of growth factor signalling in bone
Genetic determinants of osteoporosis
Non-genetic determinants of peak bone mass
Bone mineral acquisition during childhood and adolescence: physical exercise as a preventative measure
Osteoporosis in children
Pathophysiology of the Aging Skeleton
Consequences of alterations in bone remodeling
The role of parathyroid hormone and hyperparathyroidism in osteoporosis
Senile osteoporosis
Clinical Aspects of Osteoporosis
Epidemiology
Biochemical markers of bone turnover
Radiologic assessment of osteoporosis
Bone mineral density measurements
Hormone replacement therapy
Selective estrogen receptor modulators
Bisphosphonate therapy of osteoporosis
The action of fluoride on bone
PTH peptides as anabolic agents in bone
Vitamin D and Vitamin D analogs as therapeutic agents
Table of Contents provided by Publisher. All Rights Reserved.

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