γ-Adrenoceptors : signal transduction, ionic channels, and effector organs : proceedings of the 9th α-adrenoceptors conference, Tokyo, August 30-31, 1991 ; editors: Motohatsu Fujiwara, Tsuneaki Sugimoto, Kyuya Kogure.
Amsterdam : Excerpta Medica, 1992.
x, 284 p. : ill.
A Look Inside
Table of Contents
Signal transduction
Phosphorylation by nucleotide diphosphate kinase of GDP-bound [alpha]-subunits of G proteinp. 3
Role of phospholipid breakdown in signal transductionp. 15
Protein kinase C in transmembrane signaling cascadep. 31
Stimulus-transcription coupling in the nervous system: From protooncogenes to transgenesp. 42
Structure and function of the inositol 1,4,5-trisphosphate receptorp. 55
Myocardial [alpha][subscript 1]-adrenoceptor-mediated signal transduction process: Receptor subtypes and phosphoinositide hydrolysisp. 67
Mechanism of [alpha]-adrenoceptor-mediated contraction in vascular smooth musclep. 84
Possible mechanisms of the positive inotropic effect of [alpha]-adrenergic receptor stimulation in the heartp. 101
Alterations in [alpha]-adrenergic receptors in response to myocardial ischemia and their role in arrhythmogenesisp. 112
Neurotransmitter receptors after ischemic brain damagep. 127
Receptor-coupled ionic channels
Interaction between the voltage-operated calcium channel and receptor-operated nonselective cation channel in vascular smooth musclep. 141
Receptor-dependent modulation of the G protein-gated muscarinic K[superscript +] channel by arachidonic acid metabolitesp. 158
Structure and function
Desensitization of [alpha]-adrenergic receptor-mediated smooth muscle contractionp. 173
Molecular characterization of the family of [alpha]-adrenergic receptorsp. 189
A pharmacological perspective of [alpha][subscript 1]-adrenoreceptors: Subclassification and functional aspectsp. 193
Short communications
Role of [beta]-adrenergic receptors in human benign prostatic hyperplasiap. 205
Different roles of central [alpha]- and [beta]-adrenoceptors in the regulation of yawning responses in ratsp. 209
[alpha]-Adrenoceptor-mediated inhibition of endogenous norepinephrine release from vascularly perfused rat stomach in vitrop. 213
[alpha][subscript 1]-Adrenergic-mediated increase in cytosolic Ca[superscript 2+] and cyclic AMP in isolated rat hepatocytesp. 217
Purification and reconstitution of opioid receptorsp. 222
Renal adenylate cyclase-cyclic AMP system in spontaneously hypertensive rats: Effects of parathyroid hormone, prostaglandin, and [alpha][subscript 2]-adrenergic receptor stimulationp. 226
Interference of a selective mesenteric vasodilator peptide, urotensin I, with adrenergic pressor responsesp. 230
Altered cardiovascular and renal responses to central [alpha][subscript 2]-adrenoreceptor agonist (clonidine) in noninsulin-dependent diabetes mellitusp. 234
Effect of an angiotensin-converting enzyme inhibitor (enalapril) on first-dose hypotension by an [alpha][subscript 1]-adrenoreceptor blocker (bunazosin)p. 238
Pharmacological profile of the [alpha][subscript 1]-adrenoreceptor subtypesp. 241
[alpha]-Adrenoceptor subtypes in the rat skin vasculaturep. 246
Changes in inositol trisphosphate receptors of the aorta in spontaneously hypertensive ratsp. 250
Effects of endothelium- and smooth muscle-derived nitric oxide and arachidonic acid metabolites on norepinephrine-induced contraction of rat aortap. 254
Effect of exercise on adrenergic receptors of the rat heartp. 258
Decrease in [alpha][subscript 1]-adrenoreceptors during the regression of cardiac hypertrophy with angiotensin-converting enzyme inhibitorp. 262
Effect of selective [alpha][subscript 1] subtype antagonists, WB 4101 and 5-methylurapidil ([alpha][subscript 1A]-selective) or chlorethyl-clonidine ([alpha][subscript 1B]-selective), on the positive inotropic effect mediated via myocardial [alpha][subscript 1]-adrenoreceptors in the rabbit ventricular myocardiump. 266
[alpha][subscript 1]-Adrenergic signal transduction in protein synthesis in cultured neonatal rat cardiomyocytesp. 270
Abnormalities in the cardiac [alpha][subscript 1]-adrenergic receptor and its signal transduction in diabetic ratsp. 276
Modulation of norepinephrine release through [alpha][subscript 2]-adrenoreceptors at sympathetic nerve endings in congestive heart failure: Human congestive heart failure and doxorubicin-induced congestive heart failure in rabbitsp. 279
Author indexp. 283
Table of Contents provided by Blackwell. All Rights Reserved.

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