Catalogue


Cell-cell interactions : a practical approach /
edited by Bruce R. Stevenson, Warren J. Gallin, and David L. Paul.
imprint
Oxford ; New York : IRL Press at Oxford University Press, 1992.
description
xx, 304 p. : ill.
ISBN
0199633185 (pbk) : 0199633193 (h'bk) :
format(s)
Book
Holdings
More Details
imprint
Oxford ; New York : IRL Press at Oxford University Press, 1992.
isbn
0199633185 (pbk) : 0199633193 (h'bk) :
catalogue key
3203932
 
Includes bibliographical references and index.
A Look Inside
Reviews
Review Quotes
'an important but often methodologically challenging area of cell biology ... goes a long way towards demystifying the methods involved in studying cell-cell interactions in various contexts ... almost uniformly clearly written ... this book would be very useful to any newcomer to the field ofcell-cell interactions ... a rich resource in introducing the reader to the relevant literature ... it provides an excellent start towards thoughtful and successful scientific investigation of cell-cell interactions'Anne Hermanowski-Vosatka, The Rockefeller University, New York, Trends in Cell Biology, Vol. 3, August 1993
'There is a lot of valuable iinformation in this particular volume and it will certainly be of use to scientists practising in this field.'Cell Biology International, Vol. 17, No. 10, 1993
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Summaries
Long Description
Providing a wealth of practical information relating to this area of intense research in cell biology, this comprehensive volume describes the methods essential to identifying and characterizing the the molecules that mediate cellular interactions in a variety of systems. The type of communication between a cell and its immediate environment is closely related to the phenotype of that cell and the structure and function of the tissues and organs in which the cell resides. This detailed approach to cell-cell interactions includes methods for preparing relevant probes, analyzing adhesive and junctional interactions in multicellular organizations, determining which structural features of a relevant molecule are functionally important, and for assaying the consequences of cell-cell interactions in cell culture. Since the methods have applications in many related areas, this book will be invaluable to a wide range of biological scientists and students wishing to investigate the mechanisms and consequences of cellular interactions in their system of choice.
Main Description
Invaluable to a wide range of biological scientists, this book provides a wealth of practical information relating to this area of cell biology, and includes a guide to the methods essential to the identification and characterization of the molecules that mediate cellular interactions in a variety of systems.
Main Description
This book provides a wealth of practical information relating to this area of intense research in cell biology. It describes the methods essential to the identification and characterization of the molecules that mediate cellular interactions in a variety of systems. Invaluable to a wide rangeof biological scientists, the book includes methods for preparing relevant probes, analysing adhesive and junctional interactions in multicellular organizations, determining which structural features of a relevant molecule are functionally important, and for assaying the consequences of cell-cellinteractions in cell culture.
Table of Contents
Assays of Cell Adhesion
Generation and Characterization of Function-blocking Anti-cell Adhesion Molecule Antibodies
Expression Cloning: Transient Expression and Rescue From Mammalian Cells
Functional Analysis of Uvomorulin By Site-directed Mutagenesis and Gene Transfer Into Eukaryotic Cells
Integrin Mutagenesis
Isolation of Intercellular Junctions
The Xenopus Oocyte Cell-Cell Channel Assay for Functional Analysis of Gap Junction Proteins
Patch-clamp Analysis of Gap Junctional Currents
Biochemical Approaches for Analysing de novo Assembly of Epithelial Junctional Components
Biochemical Methods for Studying Supramolecular Complexes Involving Cell Adhesion Molecules
Electrophysiological Assessment of Epithelia
Compartmented Culture Analysis of Nerve Growth
Table of Contents provided by Publisher. All Rights Reserved.

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