Catalogue


Chimerism [electronic resource] : A Clinical Guide /
edited by Nicole L. Draper.
imprint
Cham : Springer International Publishing : Imprint: Springer, 2018.
description
XI, 200 p. 20 illus., 15 illus. in color. online resource.
ISBN
9783319898650 (print), 9783319898667
format(s)
Book
More Details
added author
imprint
Cham : Springer International Publishing : Imprint: Springer, 2018.
isbn
9783319898650 (print)
9783319898667
standard identifier
10.1007/978-3-319-89866-7
restrictions
Licensed for access by U. of T. users.
contents note
Fertilization and Early Embryonic Errors -- Pregnancy and Multiple Gestations -- Transplantation and Transfusion -- Relationship Testing and Forensics -- Prenatal Genetic Testing and Screening -- Blood Typing Discrepancies -- Hematopoietic Stem Cell Donor Selection and Graft-Versus-Host Disease -- Passenger Lymphocyte Syndrome -- Chimerism: A Clinical Guide to Tolerance Induction -- Autoimmune Disease -- Cancer.
abstract
This text provides a comprehensive, up-to-date review of chimerism. The first part of the volume presents the causes of chimerism, specifically focusing on fertilization and early embryonic errors, pregnancy and multiple gestations, and transplantation and transfusion. The second part of the volume outlines clinical identification and consequences of chimerism. Chapters in this section focus on the effects of chimerism on testing in relationship determination and forensics, prenatal genetic testing and screening, and blood and HLA typing. This part also reviews new data concerning matching donors and recipients for transplantation, while outlining the risks of transplantation, such as graft-vs-host disease and passenger lymphocyte syndrome. Additionally, evidence on the role of chimerism in autoimmune disease and cancer is presented. Written by experts in the field, Chimerism: A Clinical Guide is a valuable resource for clinicians and researchers that will help guide patient management and stimulate investigative efforts.
catalogue key
11807730

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