Catalogue


Gene transfer vectors for clinical application [electronic resource] /
edited by Theodore Friedman.
edition
1st ed.
imprint
Amsterdam ; Boston : Elsevier/Academic Press, 2012.
description
l, 385 p., [14] p. of plates : ill. (some col.) ; 24 cm.
ISBN
0123865093, 9780123865090
format(s)
Book
More Details
imprint
Amsterdam ; Boston : Elsevier/Academic Press, 2012.
isbn
0123865093
9780123865090
restrictions
Licensed for access by U. of T. users.
contents note
General principles of retrovirus vector design / Tammy Chang and Jiing-Kuan Yee -- Strategies for retrovirus-based correction of severe, combined immunodeficiency (SCID) / Alain Fischer, Salima Hacein-Bey-Abina, and Marina Cavazzana-Calvo -- Retrovirus and lentivirus vector design and methods of cell conditioning / Samantha Cooray, Steven J. Howe, and Adrian J. Thrasher -- Analysis of the clonal repertoire of gene-corrected cells in gene therapy / Anna Paruzynski ... [et al.] -- Developing novel lentiviral vectors into clinical products / Anna Leath and Kenneth Cornetta -- Lentivirus vectors in [beta]-thalassemia / Emmanuel Payen ... [et al.] -- Gene therapy for chronic granulomatous disease / Elizabeth M. Kang and Harry L. Malech -- Alternative splicing caused by lentiviral integration in the human genome / Arianna Moiani and Fulvio Mavilio -- Genotoxicity assay for gene therapy vectors in tumor prone mice / Eugenio Montini and Daniela Cesana -- Lentiviral hematopoietic cell gene therapy for X-linked adrenoleukodystrophy / Nathalie Cartier ... [et al.] -- Retroviral replicating vectors in cancer / Christopher R. Logg ... [et al.] -- Adeno-associated virus vectorology, manufacturing, and clinical applications / Joshua C. Grieger and R. Jude Samulski -- Gene delivery to the retina : from mouse to man / Jean Bennett, Daniel C. Chung, and Albert Maguire -- Generation of hairpin-based RNAi vectors for biological and therapeutic application / Ryan L. Boudreau and Beverly L. Davidson -- Recombinant adeno-associated viral vector reference standards / Philippe Moullier and Richard O. Snyder -- NIH oversight of human gene transfer research involving retroviral, lentiviral, and adeno-associated virus vectors and the role of the NIH Recombinant DNA Advisory Committee / Marina O'Reilly ... [et al.] -- Regulatory structures for gene therapy medicinal products in the European Union / Bettina Klug ... [et al.].
catalogue key
10757833
 
Includes bibliographical references and indexes.
A Look Inside
Summaries
Back Cover Copy
This volume of Methods in Enzymology looks at Gene Transfer Vectors for Clinical Application. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume covers such topics as General principles of retrovirus vector design, Chronic granulomatous disease (CGD), Gene therapy for blindness, and Retrovirus genetic strategy and vector design.
Bowker Data Service Summary
This volume covers topics such as the general principles of retrovirus vector design, chronic granulomatous disease, gene therapy for blindness, and retrovirus genetic strategy and vector design.
Main Description
This volume of Methods in Enzymology looks at Gene Transfer Vectors for Clinical Application. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume covers such topics as General principles of retrovirus vector design, Chronic granulomatous disease (CGD), Gene therapy for blindness, and Retrovirus genetic strategy and vector design. Chapters provide an invaluable resource for academics, researchers and students alike. Iinternational board of authors. This volume covers such topics as General principles of retrovirus vector design, Chronic granulomatous disease (CGD), Gene therapy for blindness, and Retrovirus genetic strategy and vector design.
Main Description
This volume of Methods in Enzymology looks at Gene Transfer Vectors for Clinical Application. The chapters providean invaluable resource for academics, researchers and students alike. With an international board of authors, this volume covers such topics as General principles of retrovirus vector design, Chronic granulomatous disease (CGD), Gene therapy for blindness, and Retrovirus genetic strategy and vector design. Chapters provide an invaluable resource for academics, researchers and students alikeInternational board of authorsThis volume covers such topics as general principles of retrovirus vector design, chronic granulomatous disease (CGD), gene therapy for blindness, and retrovirus genetic strategy and vector design
Main Description
This volume of Methods in Enzymology looks at Gene Transfer Vectors for Clinical Application. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume covers such topics as General principles of retrovirus vector design, Chronic granulomatous disease (CGD), Gene therapy for blindness, and Retrovirus genetic strategy and vector design. Chapters provide an invaluable resource for academics, researchers and students alike International board of authors This volume covers such topics as general principles of retrovirus vector design, chronic granulomatous disease (CGD), gene therapy for blindness, and retrovirus genetic strategy and vector design
Table of Contents
Preface: The successful clinical use of viral vectors for human gene therapy
General principles of retrovirus vector design
Strategies for retrovirus-based correction of severe, combined immunodeficiency (SCID)
Retrovirus and lentivirus vector design and methods of cell conditioning
Analysis of the clonal repertoire of gene corrected cells in gene therapy
Developing novel lentiviral vectors into clinical products
Lentivirus vectors in beta-thalassemia
Gene Therapy for Chronic Granulomatous Disease
Alternative splicing caused by lentiviral integration in the human genome
Genotoxicity assay for gene therapy vectors in tumor prone Cdkn2a-/- mice
Lentiviral Hematopoietic Cell Gene Therapy for X-linked Adrenoleukodystrophy
Retroviral replicating vectors in cancer
Adeno-associated virus vectorology, manufacturing and clinical applications
Gene Delivery To The Retina: From Mouse To Man
Generation of hairpin-based RNAi vectors for biological and therapeutic application
Recombinant adeno-associated viral vector reference standards
NIH oversight of human gene transfer research involving retroviral, lentiviral and adeno-associated virus vectors and the role of the NIH recombinant DNA advisory committee draft
Regulatory structures for gene therapy medicinal products in the European Union
Table of Contents provided by Publisher. All Rights Reserved.

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