Catalogue


The childhood immunization schedule and safety : stakeholder concerns, scientific evidence, and future studies /
Committee on the Assessment of Studies of Health Outcomes Related to the Recommended Childhood Immunization Schedule, Board on Population Health and Public Health Practice, Institute of Medicine of the National Academies.
imprint
Washington, D.C. : National Academies Press, c2013.
description
xv, 219 p. : ill. ; 23 cm.
ISBN
0309267021, 9780309267021
format(s)
Book
Holdings
More Details
imprint
Washington, D.C. : National Academies Press, c2013.
isbn
0309267021
9780309267021
contents note
Introduction -- Determination of the immunization schedule -- Existing data sources and systems -- Stakeholder concerns related to the safety of the immunization schedule -- Review of scientific findings -- Methodological approaches to studying health outcomes associated with the current immunization schedule: options, feasibility, ethical issues, and priorities -- Conclusions and recommendations.
abstract
"The Childhood Immunization Schedule and Safety: Stakeholder Concerns, Scientific Evidence, and Future Studies reviews scientific findings and stakeholders concerns related to the safety of the recommended childhood immunization schedule. This report also identifies potential research approaches, methodologies and study designs that could inform this question, considering strengths, weaknesses as well as ethical and financial feasibility of each approach. This report draws on data from existing surveillance systems, such as the Vaccine Safety Datalink, could be used and offers the best means for ongoing research efforts regarding the safety of the schedule. In recognition of this, future federal research approaches should: collect and assess evidence regarding public confidence in and concerns about the entire childhood immunization schedule, with the goal to improve communication with health care professionals, and between health care professionals and the public regarding safety; standardize definitions of key elements of the schedule, and relevant health outcomes; establish research priorities on the basis of epidemiological evidence, biological plausibility, and feasibility; and continue to fund and support the Vaccine Safety Datalink project to study the safety of the recommended immunization schedule"--Publisher's description.
catalogue key
10373213
 
Also issued online.
Includes bibliographical references.
A Look Inside
Summaries
Long Description
The Childhood Immunization Schedule and Safety: Stakeholder Concerns, Scientific Evidence, and Future Studies reviews scientific findings and stakeholders concerns related to the safety of the recommended childhood immunization schedule. This report also identifies potential research approaches, methodologies and study designs that could inform this question, considering strengths, weaknesses as well as ethical and financial feasibility of each approach. This report draws on data from existing surveillance systems, such as the Vaccine Safety Datalink, could be used and offers the best means for ongoing research efforts regarding the safety of the schedule. In recognition of this, future federal research approaches should: collect and assess evidence regarding public confidence in and concerns about the entire childhood immunization schedule, with the goal to improve communication with health care professionals, and between health care professionals and the public regarding safety; standardize definitions of key elements of the schedule, and relevant health outcomes; establish research priorities on the basis of epidemiological evidence, biological plausibility, and feasibility; and continue to fund and support the Vaccine Safety Datalink project to study the safety of the recommended immunization schedule.
Table of Contents
Abstractp. xiv
Summaryp. 1
Introductionp. 17
Study Backgroundp. 20
Committee on the Assessment of Studies of Health Outcomes Related to the Recommended Childhood Immunization Schedulep. 20
Committee Processp. 21
Previous IOM Vaccine Studiesp. 22
Organization of the Reportp. 23
Referencesp. 23
Determination of the Immunization Schedulep. 25
Immune System Responsesp. 25
Immunization at the Population Levelp. 28
Immunization Policyp. 30
Vaccine Development and Approval Specificsp. 31
Past and Present Immunization Schedulesp. 34
Referencesp. 37
Existing Data Sources and Systemsp. 39
Immunization Safety Surveillancep. 39
Databases Used to Assess Coveragep. 46
Databases Examining Adverse Events After Immunization for Vaccine-Preventable Diseasesp. 48
Immunization Data Systems in Other Countriesp. 50
Referencesp. 54
Stakeholder Concerns Related to the Safety of the Immunization Schedulep. 59
Identification of Stakeholdersp. 60
Information Gatheringp. 61
Literature Searchp. 61
Parental Concerns in the Scientific Literaturep. 62
Public Concerns Presented to the Committeep. 65
Patient-Provider Communicationp. 66
Conclusionsp. 68
Referencesp. 72
Review of Scientific Findingsp. 75
Literature Search Methodsp. 76
Literature Summaryp. 78
Conclusionsp. 94
Referencesp. 95
Methodological Approaches to Studying Health Outcomes Associated with the Current Immunization Schedule: Options, Feasibility, Ethical Issues, and Prioritiesp. 99
Considerations to Determine Need for Initiation of New Studiesp. 100
Potential Research Questions of Interestp. 103
General Research Approaches to Address Primary Research Questions of Interestp. 105
Methods to Monitor Community Immunity and Measure Population-Level Impacts of Studies of the Immunization Schedulep. 119
Conclusionsp. 122
Referencesp. 123
Conclusions and Recommendationsp. 127
Committee Response to Its Statement of Taskp. 127
Concluding Observationsp. 135
Referencesp. 136
Appendixes
2012 Advisory Committee on Immunization Practices' Recommended Immunization Schedule for Childrenp. 137
Glossaryp. 145
Acronymsp. 157
Study Designs for the Safety Evaluation of Different Childhood Immunization Schedules, Martin Kulldorffp. 161
Agendas of Public Meetings Held by the Committeep. 201
Biographical Sketches of Committee Membersp. 207
Institute of Medicine Publications on Vaccinesp. 217
Table of Contents provided by Ingram. All Rights Reserved.

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