Peripheral receptor targets for analgesia : novel approaches to pain treatment /
edited by Brian E. Cairns.
imprint
Hoboken, N.J. : John Wiley & Sons, c2009.
description
xiii, 541 p.
ISBN
047025131X (cloth), 9780470251317 (cloth)
format(s)
Book
Holdings
More Details
added author
imprint
Hoboken, N.J. : John Wiley & Sons, c2009.
isbn
047025131X (cloth)
9780470251317 (cloth)
contents note
Role of peripheral mechanisms in craniofacial pain conditions / Barry J. Sessle -- Role of peripheral mechanisms in spinal pain conditions / Brian E. Cairns & Pradit Prateepavanich -- Voltage-gated sodium channels in peripheral nociceptive neurons as targets for the treatment of pain / Theodore R. Cummins -- Potassium channels / Daisuke Nishizawa1, Toru Kobayashi, & Kazutaka Ikeda -- Voltage-gated calcium channels as targets for the treatment of chronic pain / Joe McGivern -- Adenosine receptors / Jana Sawynok -- Acid-sensing ion channels and pain / Roxanne Y. Walder, Christopher J. Benson & Kathleen A. Sluka -- Vanilloid (TRPV1) and other transient receptor potential channels / Marcello Trevisani & Arpad Szallasi -- Glutamate receptors / Brian E. Cairns -- Serotonin receptors / Malin Ernberg -- Adrenergic receptors / Antti Pertovaara -- Cholinergic receptors and botulinum toxin / Parisa Gazerani -- Cannabinoids and pain control in the periphery / Jason J. McDougall -- Opioid receptors / Claudia Herrera Tambeli, Luana Fischer & Carlos Amilcar Parada -- Calcitonin gene-related peptide and substance P / Ranjinidevi Ambalavanar & Dean Dessem -- Role of somatostatin and somatostatin receptors in pain / Ujendra Kumar -- Cytokines (tumor necrosis factor, interleukins) and prostaglandins / Per Alstergren -- Neurotrophic factors and pain / Peter Svensson -- Topical and systemic dosage forms for targeted drug delivery / Urs Hafeli & Amit Kale -- Gene therapy for pain / Marina Mata & David J. Fink -- Topical analgesics / Akhlaq Waheed Hakim & Brian E. Cairns.
general note
Includes index.
catalogue key
6922937
A Look Inside
Reviews
This item was reviewed in:
SciTech Book News, December 2009
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Summaries
Bowker Data Service Summary
This work reviews the role of peripheral receptor mechanisms in the transduction of pain, providing a framework for the development of new and effective rationally-designed analgesic drugs and therapies. It brings together in one text the diverse body of work on peripheral receptor mechanisms of pain.
Main Description
A unique reference on peripheral pain receptor mechanisms While considerable advances have been made on pharmacotherapies for many chronic disease states, options available to treat chronic pain have remained relatively unchanged for decades. However, utilizing the receptors involved in peripheral pain transduction mechanisms offers a significant opportunity to create novel therapies for pain. A comprehensive review of peripheral pain mechanisms, Peripheral Receptor Targets for Analgesia: Novel Approaches to Pain Management provides a unique resource that brings together a body of knowledge that was previously widely dispersed. As such, it gives readers a framework for further basic and clinical studies on potential receptor targets, as well as the development of improved topical analgesics. Coverage includes: The latest discoveries by leading researchers relating to the function of various ion channels and receptors in the peripheral nervous system Novel delivery techniques An appendix listing currently available topical analgesic medications A Foreword by Professor Lars Arendt-Nielsen of the Center for Sensory-Motor Interaction (SMI) at Aalborg University An unmatched resource for improving drug therapies and making pain management more efficient, Peripheral Receptor Targets for Analgesia supplies pharmaceutical scientists, pharmacologists, neuroscientists, and graduate and upper-level undergraduate students with a comprehensive, up-to-date reference.
Main Description
A unique reference on peripheral pain receptor mechanismsWhile considerable advances have been made on pharmacotherapies for many chronic disease states, options available to treat chronic pain have remained relatively unchanged for decades. However, utilizing the receptors involved in peripheral pain transduction mechanisms offers a significant opportunity to create novel therapies for pain.A comprehensive review of peripheral pain mechanisms, Peripheral Receptor Targets for Analgesia: Novel Approaches to Pain Management provides a unique resource that brings together a body of knowledge that was previously widely dispersed. As such, it gives readers a framework for further basic and clinical studies on potential receptor targets, as well as the development of improved topical analgesics.Coverage includes:The latest discoveries by leading researchers relating to the function of various ion channels and receptors in the peripheral nervous systemNovel delivery techniquesAn appendix listing currently available topical analgesic medicationsA Foreword by Professor Lars Arendt-Nielsen of the Center for Sensory-Motor Interaction (SMI) at Aalborg UniversityAn unmatched resource for improving drug therapies and making pain management more efficient, Peripheral Receptor Targets for Analgesia supplies pharmaceutical scientists, pharmacologists, neuroscientists, and graduate and upper-level undergraduate students with a comprehensive, up-to-date reference.
Main Description
Peripheral Receptor Targets for AnalgesiaNovel Approaches to Pain ManagementEdited byBrian E. CairnsA unique reference on peripheral pain receptor mechanismsWhile considerable advances have been made on pharmacotherapies for many chronic disease states, options available to treat chronic pain have remained relatively unchanged for decades. However, utilizing the receptors involved in peripheral pain transduction mechanisms offers a significant opportunity to create novel therapies for pain.A comprehensive review of peripheral pain mechanisms, Peripheral Receptor Targets for Analgesia: Novel Approaches to Pain Management provides a unique resource that brings together a body of knowledge that was previously widely dispersed. As such, it gives readers a framework for further basic and clinical studies on potential receptor targets, as well as the development of improved topical analgesics.Coverage includes:The latest discoveries by leading researchers relating to the function of various ion channels and receptors in the peripheral nervous systemNovel delivery techniquesAn appendix listing currently available topical analgesic medicationsA Foreword by Professor Lars Arendt-Nielsen of the Center for Sensory-Motor Interaction (SMI) at Aalborg UniversityAn unmatched resource for improving drug therapies and making pain management more efficient, Peripheral Receptor Targets for Analgesia supplies pharmaceutical scientists, pharmacologists, neuroscientists, and graduate and upper-level undergraduate students with a comprehensive, up-to-date reference.
Main Description
Peripheral Receptor Targets for Analgesia reviews the role of peripheral receptor mechanisms in the transduction of pain, providing a framework for the development of new and effective rationally-designed analgesic drugs and therapies with and promoting further basic and clinical studies on potentially interesting peripheral receptor targets. It uniquely brings together in one text the diverse body of work on peripheral receptor mechanisms of pain. This comprehensive reference aids pharmaceutical scientists, pharmacologists, and neuroscientists developing drugs and researching pain in achieving selectivity in drug therapy for more efficient pain management.
Table of Contents
Peripheral Mechanism In Clinical Pain Conditions
Role of Peripheral Mechanisms in Craniofacial Pain Conditions
Role of Peripheral Mechanisms in Spinal Pain Conditions
Specific Receptor Targets For Peripheral Analgesics
Voltage-gated sodium channels in peripheral nociceptive neurons as targets for the treatment of pain
Potassium Channels
Voltage-gated calcium channels as targets for the treatment of chronic pain
Adenosine Receptors
Acid-Sensing Ion Channels and Pain
Vanilloid (TRPV1) and other transient receptor potential channels
Glutamate Receptors
Serotonin Receptors
Adrenergic Receptors
Cholinergic Receptors and Botulinum Toxin
Cannabinoids and Pain Control in the Periphery
Opioid Receptors
Calcitonin Gene-Related Peptide and Substance
Role of Somatostatin and Somatostatin Receptors in Pain
Cytokines Tumor Necrosis Factor, Interleukins and Prostaglandins
Neurotrophic factors and pain
Delivery Systems
Topical and Systemic Dosage Forms for Targeted Drug delivery
Gene Therapy for Pain
Topical Analgesics
Table of Contents provided by Publisher. All Rights Reserved.

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